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儿童哮喘共病焦虑和抑郁及其对症状控制的影响:一项横断面研究。

Co-morbid anxiety and depression in childhood asthma and its effect on symptom control: A cross sectional study.

机构信息

Department of Pediatrics, JIPMER, Puducherry, India.

Department of Psychiatry, JIPMER, Puducherry, India.

出版信息

Pediatr Pulmonol. 2021 Feb;56(2):378-383. doi: 10.1002/ppul.25180. Epub 2020 Nov 27.

Abstract

BACKGROUND

Anxiety and depression are co-morbidities that affect symptom control in children with asthma and are often overlooked in busy practice.

OBJECTIVES

To find out the proportion of children with asthma who have co-morbid anxiety and depression, to study the association of co-morbid anxiety and depression on symptom control and to study the clinic-sociodemographic factors associated with anxiety and depression in children with asthma.

METHODS

Assuming 13% prevalence of anxiety and depression, with 95% confidence level and 5% absolute precision, a total of 176 children with asthma aged 6 years and above were enrolled from the asthma clinic. Clinical and sociodemographic details were collected for all. Symptom control was assessed using asthma control test questionnaire. Center for epidemiological studies-depression scale for children and screen for child anxiety related emotional disorders was used to assess depression and anxiety, respectively. Association of independent variables with outcome variables was assessed using χ . Statistical tests were done using SPSS version 26.

RESULTS

Out of the 176 children enrolled, 13.1%, 8%, and 16.5% had anxiety, depression, and combined anxiety and depression, respectively. A higher proportion of children with uncontrolled asthma had depression and combined anxiety and depression than children with controlled asthma.

CONCLUSION

Combined anxiety and depression was more common than either anxiety or depression alone and along with depression, was significantly associated with uncontrolled symptoms.

摘要

背景

焦虑和抑郁是共病,会影响哮喘儿童的症状控制,而在繁忙的临床实践中,这些共病往往被忽视。

目的

了解合并焦虑和抑郁的哮喘儿童的比例,研究合并焦虑和抑郁对症状控制的影响,并研究与哮喘儿童焦虑和抑郁相关的临床和社会人口学因素。

方法

假设焦虑和抑郁的患病率为 13%,置信水平为 95%,绝对精度为 5%,我们从哮喘诊所招募了 176 名年龄在 6 岁及以上的哮喘儿童。收集所有儿童的临床和社会人口学资料。使用哮喘控制测试问卷评估症状控制。使用儿童流行病学研究中心抑郁量表和儿童焦虑相关情绪障碍筛查量表分别评估抑郁和焦虑。使用 χ 检验评估自变量与因变量的关联。统计分析使用 SPSS 版本 26。

结果

在纳入的 176 名儿童中,分别有 13.1%、8%和 16.5%的儿童患有焦虑症、抑郁症和焦虑与抑郁共病。与控制良好的哮喘儿童相比,控制不佳的哮喘儿童中患有抑郁症和焦虑与抑郁共病的比例更高。

结论

与单独的焦虑或抑郁相比,焦虑与抑郁共病更为常见,且与抑郁一样,与未控制的症状显著相关。

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