Department of Food Science and Engineering, Ningbo University, Ningbo, P.R. China.
Department of Food Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
J Food Biochem. 2021 Jan;45(1):e13575. doi: 10.1111/jfbc.13575. Epub 2020 Nov 21.
Tea polyphenols (TP) are important functional components in tea. TP can regulate the composition of human intestinal flora, meanwhile, TP can be bio-transformed by the intestinal microbiota, resulting in relative metabolites, which prevent nerve damage, promote neurocognition, and increase resistance to oxidative stress. In recent years, cerebral nerves have become a hot topic of research, and studies have marked the importance of microbial flora and TP in protecting cerebral nerves. This paper reviews the effects of TP on intestinal microflora and the microbial degradation of TP. Furthermore, the potential effects of TP on cerebral nerves have been highlighted. PRACTICAL APPLICATIONS: Neuroscience studies are primarily focused on discerning the functional mechanism of the nervous system. The functional role of intestinal microbiota in host physiology regulation, especially neurological functions, has become a hotspot for neurological research. TP play a vital role in maintaining the steady status of intestinal flora and protecting cerebral nerve damage. An in-depth understanding of the TP and intestinal microbiota interaction, its implication on cerebral nerve protection, and the associated underlying mechanism will allow us to expand the therapeutic applications of TP.
茶多酚（TP）是茶叶中的重要功能成分。TP 可以调节人体肠道菌群的组成，同时，TP 可以被肠道微生物群生物转化，产生相对代谢物，从而预防神经损伤、促进神经认知、增加抗氧化应激能力。近年来，大脑神经已成为研究热点，研究表明微生物菌群和 TP 对保护大脑神经具有重要意义。本文综述了 TP 对肠道微生物群的影响及其微生物降解 TP 的作用。此外，还强调了 TP 对大脑神经的潜在影响。
神经科学研究主要集中在辨别神经系统的功能机制上。肠道微生物群在宿主生理调节中的功能作用，特别是在神经功能方面，已成为神经科学研究的热点。TP 在维持肠道菌群的稳定状态和保护大脑神经损伤方面发挥着重要作用。深入了解 TP 与肠道微生物群的相互作用、对大脑神经保护的影响及其相关的潜在机制，将有助于拓展 TP 的治疗应用。
