Department of Food Science and Engineering, Ningbo University, Ningbo 315211, P.R. China.
Department of Food Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA.
Food Funct. 2021 Feb 15;12(3):952-962. doi: 10.1039/d0fo02791j.
Tea polyphenols (TP) are the most bioactive components in tea extracts. It has been reported that TP can regulate the composition and the function of the intestinal flora. Meanwhile, intestinal microorganisms improve the bioavailability of TP, and the corresponding metabolites of TP can regulate intestinal micro-ecology and promote human health more effectively. The dysfunction of the microbiota-gut-brain axis is the main pathological basis of depression, and its abnormality may be the direct cause and potential influencing factor of psychiatric disorders. The interrelationship between TP and intestinal microorganisms is discussed in this review, which will enable us to better evaluate the potential preventive effects of TP on psychiatric disorders by modulating host intestinal microorganisms.
茶多酚（TP）是茶叶提取物中最具生物活性的成分。据报道，TP 可以调节肠道菌群的组成和功能。同时，肠道微生物可以提高 TP 的生物利用度，TP 的相应代谢物可以更有效地调节肠道微生态，促进人体健康。微生物-肠道-大脑轴的功能障碍是抑郁症的主要病理基础，其异常可能是精神疾病的直接原因和潜在影响因素。本综述讨论了 TP 与肠道微生物之间的相互关系，这将使我们能够更好地通过调节宿主肠道微生物来评估 TP 对精神疾病的潜在预防作用。
