宿主昼夜节律与肠道微生物群的关系：茶多芬通过改善健康的新线索。
The relationship between host circadian rhythms and intestinal microbiota: A new cue to improve health by tea polyphenols.
机构信息
Department of Food Science and Engineering, Ningbo University, Ningbo University, Ningbo, P.R. China.
Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.
出版信息
Crit Rev Food Sci Nutr. 2021;61(1):139-148. doi: 10.1080/10408398.2020.1719473. Epub 2020 Jan 30.
Under the control of the host circadian rhythms, intestinal microbiota undergoes dietary-dependent diurnal fluctuations in composition and function. In addition, microbiome plays a critical role in maintaining the host circadian rhythms and metabolic homeostasis. The interactions between host circadian rhythms and intestinal microbiota suggest that intervention with prebiotics or probiotic is a possible way to alleviate circadian rhythm misalignment and related metabolic diseases. This review discusses the circadian rhythm oscillations of gut flora, relationship between host circadian rhythms and microbiome and related effects on metabolism. The influence on circadian rhythms by the interactions between tea polyphenols (TP) and intestinal microbiota is highlighted.
在宿主生物钟的控制下，肠道微生物群的组成和功能会随饮食发生昼夜波动。此外，微生物组在维持宿主生物钟和代谢稳态方面起着关键作用。宿主生物钟与肠道微生物群之间的相互作用表明，通过干预益生元和益生菌可能是缓解生物钟失调和相关代谢疾病的一种方法。本综述讨论了肠道菌群的生物钟波动、宿主生物钟与微生物组的关系以及对代谢的相关影响。强调了茶多酚（TP）与肠道微生物群相互作用对生物钟的影响。
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