College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo, P.R. China.
J Food Biochem. 2019 Aug;43(8):e12953. doi: 10.1111/jfbc.12953. Epub 2019 Jun 17.
Tea polyphenols (TP) is the main functional substances in tea. It has been reported that TP can modulate the composition of gut microbes in the human body, in addition, after the bio-transformation by intestinal flora, the metabolites of TP also have positive effects on the health of the host. Lots of researches have shown that TP have possible therapeutic effect against high fat diet induced obesity, which is closely related to the gut flora of the host. Therefore, this review focused on the interactions of TP with intestinal microbiota and their implication for cellular signal conditioning mechanism that will enable us to better study the two-way effects of TP and intestinal microbiota on host health improvement. PRACTICAL APPLICATIONS: TP have been widely concerned for their health care properties. As the functional food components, TP have strong antioxidant and physiological activities for human body. A better understanding on the interactions of TP with intestinal microbiota and their implication for cellular signal conditioning mechanism will lead us to better evaluate the contribution of the microbial metabolites of TP, as well as the regulation of intestinal bacterial diversity and abundance for host health.
茶多酚（TP）是茶叶中的主要功能物质。据报道，TP 可以调节人体肠道微生物的组成，此外，肠道菌群对 TP 进行生物转化后，TP 的代谢产物也对宿主的健康有积极作用。大量研究表明，TP 对高脂肪饮食诱导的肥胖具有潜在的治疗作用，这与宿主的肠道菌群密切相关。因此，本综述重点讨论了 TP 与肠道微生物群的相互作用及其对细胞信号调节机制的影响，这将使我们能够更好地研究 TP 和肠道微生物群对宿主健康改善的双向作用。
TP 因其对健康的有益特性而受到广泛关注。作为功能性食品成分，TP 具有很强的抗氧化作用和对人体的生理活性。更好地了解 TP 与肠道微生物群的相互作用及其对细胞信号调节机制的影响，将有助于我们更好地评估 TP 的微生物代谢产物的贡献，以及肠道细菌多样性和丰度对宿主健康的调节。
