Mizrahi Michelle, Jimenez-Becerra Silvia, Rivera-Navarrete Eric, Gomez-Sanchez Mario
General Physician, National Institute of Cardiology "Ignacio Chavez" Juan Badiano 1, 5to piso, Col. Seccion XVI, Tlalpan, CP 14080 Mexico City, Mexico.
Attending Pathologist, National Institute of Cardiology "Ignacio Chavez" Juan Badiano 1, 5to piso, Col. Seccion XVI, Tlalpan, CP 14080 Mexico City, Mexico.
Am J Cardiovasc Dis. 2020 Oct 15;10(4):382-385. eCollection 2020.
Although uncommon, Libman-Sack endocarditis is the most characteristic cardiac manifestation of Systemic Lupus Erythematosus (SLE). It forms vegetations made of inflammatory tissue on the cardiac valves, leading them to malfunction. Here we present a case of a young woman who presented with severe mitral valve regurgitation in need for a valve replacement. Integral evaluation of the patient revealed the diagnosis of SLE, which was aggressively treated in an outpatient setting with immunosuppressive therapy. Only after achieving medical stabilization of the underlying disease, she was able to undergo surgical mitral valve replacement. After the surgery, the patient no longer suffered from mitral regurgitation, and with a mechanical prosthesis in place, the risk of Libman-Sacks endocarditis recurrence is thought to be minimal.
尽管罕见，但Libman-Sack心内膜炎是系统性红斑狼疮（SLE）最典型的心脏表现。它在心脏瓣膜上形成由炎性组织构成的赘生物，导致瓣膜功能异常。在此，我们报告一例年轻女性患者，该患者因严重二尖瓣反流而需要进行瓣膜置换。对该患者的全面评估显示其患有SLE，并在门诊环境中采用免疫抑制疗法进行了积极治疗。仅在基础疾病实现医学稳定后，她才得以接受二尖瓣置换手术。手术后，患者不再患有二尖瓣反流，并且由于植入了机械假体，Libman-Sacks心内膜炎复发的风险被认为极小。
