• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).

作者信息

Bale Tejus A, Sait Sameer F, Benhamida Jamal, Ptashkin Ryan, Haque Sofia, Villafania Liliana, Sill Martin, Sadowska Justyna, Akhtar Razia B, Liechty Benjamin, Juthani Rupa, Ladanyi Marc, Fowkes Mary, Karajannis Matthias A, Rosenblum Marc K

机构信息

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

出版信息

Acta Neuropathol. 2021 Jan;141(1):123-125. doi: 10.1007/s00401-020-02245-4. Epub 2020 Nov 23.

DOI:10.1007/s00401-020-02245-4
PMID:33226472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8493813/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eba/8493813/9f8b66c3a4c1/nihms-1737247-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eba/8493813/9f8b66c3a4c1/nihms-1737247-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eba/8493813/9f8b66c3a4c1/nihms-1737247-f0001.jpg

相似文献

1
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).青少年多形性低级别神经上皮肿瘤（PLNTY）的恶性转化
Acta Neuropathol. 2021 Jan;141(1):123-125. doi: 10.1007/s00401-020-02245-4. Epub 2020 Nov 23.
2
Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations.年轻患者的多形性低级别神经上皮肿瘤：病例报告并重点关注影像学特征和遗传改变。
BMC Neurol. 2020 Apr 6;20(1):123. doi: 10.1186/s12883-020-01679-3.
3
Polymorphous low-grade neuroepithelial tumor of the young: case report of a newly described histopathological entity.青少年多形性低度恶性神经上皮肿瘤：一种新描述的组织病理学实体的病例报告
Acta Neurol Belg. 2020 Jun;120(3):729-732. doi: 10.1007/s13760-019-01241-0. Epub 2019 Nov 21.
4
Polymorphous Low-Grade Neuroepithelial Tumor of the Young: A Case Report with Genomic Findings.年轻患者多形性低级别神经上皮肿瘤：伴有基因组发现的病例报告。
World Neurosurg. 2019 Dec;132:347-355. doi: 10.1016/j.wneu.2019.08.221. Epub 2019 Sep 11.
5
Malignant Astroblastoma.恶性成星形细胞瘤
Balkan Med J. 2020 Jun 1;37(4):224-225. doi: 10.4274/balkanmedj.galenos.2020.2019.11.39. Epub 2020 Mar 26.
6
Polymorphous low-grade neuroepithelial tumour of young (PLNTY): the new kid on the block.年轻多形性低级别神经上皮肿瘤（PLNTY）：新的街区小孩。
Childs Nerv Syst. 2024 Feb;40(2):555-561. doi: 10.1007/s00381-023-06162-1. Epub 2023 Oct 5.
7
[Cerebral astroblastoma: report of a case and literature review].
Neurocirugia (Astur). 2002 Oct;13(5):378-84; discussion 384. doi: 10.1016/s1130-1473(02)70591-5.
8
Case Report of Rarely Described Polymorphous Low-Grade Neuroepithelial Tumor of the Young and Comparison with Oligodendroglioma.年轻患者中罕见的多形性低级别神经上皮肿瘤病例报告，并与少突胶质细胞瘤进行比较。
World Neurosurg. 2019 Jul;127:47-51. doi: 10.1016/j.wneu.2019.03.181. Epub 2019 Mar 26.
9
Dysembryoplastic neuroepithelial tumor transforming into malignancy: a case report.
Neurol India. 2014 May-Jun;62(3):323-5. doi: 10.4103/0028-3886.137011.
10
Radiological and surgical aspects of polymorphous low-grade neuroepithelial tumor of the young (PLNTY).年轻患者多形性低级别神经上皮肿瘤的放射学和外科方面。
Acta Neurol Belg. 2023 Apr;123(2):327-340. doi: 10.1007/s13760-023-02231-z. Epub 2023 Mar 10.

引用本文的文献

1
Polymorphous low-grade neuroepithelial tumor of the young.青少年多形性低度恶性神经上皮肿瘤
Surg Neurol Int. 2025 Jul 25;16:300. doi: 10.25259/SNI_1061_2024. eCollection 2025.
2
Illuminating radiogenomic signatures in pediatric-type diffuse gliomas: insights into molecular, clinical, and imaging correlations. Part II: low-grade group.小儿型弥漫性胶质瘤中的放射基因组学特征解读：分子、临床及影像相关性洞察。第二部分：低级别组
Radiol Med. 2025 Jul 16. doi: 10.1007/s11547-025-02049-0.
3
A rare tumor with unique features: polymorphous low-grade neuroepithelial tumor of the young with third ventricular location and TP53 mutation. Illustrative case.

本文引用的文献

1
Polymorphous Low-Grade Neuroepithelial Tumor of the Young: A Case Report with Genomic Findings.年轻患者多形性低级别神经上皮肿瘤：伴有基因组发现的病例报告。
World Neurosurg. 2019 Dec;132:347-355. doi: 10.1016/j.wneu.2019.08.221. Epub 2019 Sep 11.
2
A newly diagnosed case of polymorphous low-grade neuroepithelial tumor of the young.一例新诊断的年轻型多形性低度神经上皮肿瘤病例。
Clin Neuropathol. 2018 Jul-Aug;37(4):178-181. doi: 10.5414/NP301081.
3
DNA methylation-based classification of central nervous system tumours.基于 DNA 甲基化的中枢神经系统肿瘤分类。
一种具有独特特征的罕见肿瘤：发生于年轻人的多形性低度神经上皮肿瘤，位于第三脑室并伴有TP53突变。病例说明。
J Neurosurg Case Lessons. 2025 Jul 14;10(2). doi: 10.3171/CASE25346.
4
Phenotypic and epigenetic heterogeneity in FGFR2-fused glial and glioneuronal tumours.FGFR2 融合型神经胶质和神经胶质神经元肿瘤的表型和表观遗传异质性。
Neuropathol Appl Neurobiol. 2024 Dec;50(6):e13014. doi: 10.1111/nan.13014.
5
Paediatric low-grade glioma: the role of classical pathology in integrated diagnostic practice.小儿低度神经胶质瘤：经典病理学在综合诊断实践中的作用。
Childs Nerv Syst. 2024 Oct;40(10):3189-3207. doi: 10.1007/s00381-024-06591-6. Epub 2024 Sep 18.
6
MAPK pathway alterations in polymorphous low-grade neuroepithelial tumor of the young: diagnostic considerations.年轻患者多形性低级别神经上皮肿瘤中 MAPK 通路改变：诊断注意事项。
Brain Tumor Pathol. 2024 Oct;41(3-4):109-116. doi: 10.1007/s10014-024-00487-8. Epub 2024 Aug 18.
7
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Scoping Review of Case Reports and Case Series.青少年多形性低度神经上皮肿瘤（PLNTY）：病例报告和病例系列的范围综述
Asian J Neurosurg. 2024 May 27;19(2):126-136. doi: 10.1055/s-0044-1786700. eCollection 2024 Jun.
8
Second-look surgery in postoperative pediatric low-grade glioma.术后小儿低度胶质瘤的二次探查手术。
Childs Nerv Syst. 2024 Oct;40(10):3135-3142. doi: 10.1007/s00381-024-06516-3. Epub 2024 Jul 6.
9
Diffuse Gliomas with :: Fusion: Morphological and Molecular Features and Classification Challenges.伴有融合的弥漫性胶质瘤：形态学和分子特征及分类挑战
Cancers (Basel). 2024 Apr 25;16(9):1644. doi: 10.3390/cancers16091644.
10
Expanding the Imaging Spectrum of Polymorphous Low-Grade Neuroepithelial Tumor of the Young in Children.扩展儿童多形性低级别神经上皮肿瘤的影像学谱。
AJNR Am J Neuroradiol. 2024 Apr 8;45(4):483-487. doi: 10.3174/ajnr.A8145.
Nature. 2018 Mar 22;555(7697):469-474. doi: 10.1038/nature26000. Epub 2018 Mar 14.
4
Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features.具有 FGFR3-TACC3 融合的弥漫性神经胶质瘤具有特征性的组织病理学和分子特征。
Brain Pathol. 2018 Sep;28(5):674-683. doi: 10.1111/bpa.12563. Epub 2017 Nov 21.
5
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.青少年多形性低度神经上皮肿瘤（PLNTY）：一种具有少突胶质细胞瘤样成分、异常CD34表达以及涉及丝裂原活化蛋白激酶（MAP）激酶途径的基因改变的致癫痫肿瘤。
Acta Neuropathol. 2017 Mar;133(3):417-429. doi: 10.1007/s00401-016-1639-9. Epub 2016 Nov 3.
6
FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing.FACETS：用于高通量DNA测序的等位基因特异性拷贝数和克隆异质性分析工具。
Nucleic Acids Res. 2016 Sep 19;44(16):e131. doi: 10.1093/nar/gkw520. Epub 2016 Jun 7.
7
Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.罕见低级别神经上皮肿瘤中的基因改变：BRAF、FGFR1和MYB突变高频发生且与形态学相符。
Acta Neuropathol. 2016 Jun;131(6):833-45. doi: 10.1007/s00401-016-1539-z. Epub 2016 Jan 25.
8
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.纪念斯隆凯特琳癌症中心可操作癌症靶点综合突变分析（MSK-IMPACT）：一种基于杂交捕获的实体瘤分子肿瘤学新一代测序临床检测方法。
J Mol Diagn. 2015 May;17(3):251-64. doi: 10.1016/j.jmoldx.2014.12.006. Epub 2015 Mar 20.
9
Anchored multiplex PCR for targeted next-generation sequencing.靶向下一代测序的锚定多重 PCR。
Nat Med. 2014 Dec;20(12):1479-84. doi: 10.1038/nm.3729. Epub 2014 Nov 10.
10
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.全基因组测序鉴定小儿低级别胶质瘤中的遗传改变。
Nat Genet. 2013 Jun;45(6):602-12. doi: 10.1038/ng.2611. Epub 2013 Apr 14.