Murphy S
Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque.
Clin Chest Med. 1987 Dec;8(4):695-710.
Once regarded as a disease of infants and young children, cystic fibrosis now also must be considered a disease of adolescents and young adults. Disease complications and management, including hemoptysis, pneumothorax, sinusitis, pancreatic deficiency, and intestinal obstruction, are discussed in this review. In addition, a practical approach to the clinical evaluation, follow-up, and treatment of the older cystic fibrosis patient is presented for the physician who has not had extensive experience in managing these patients. Current research in identifying the CF gene, basic defect, and the use of heart-lung transplants is discussed.
囊性纤维化曾一度被视为婴幼儿疾病，如今也必须被视作青少年和青年成人的疾病。本综述讨论了疾病并发症及管理，包括咯血、气胸、鼻窦炎、胰腺功能不全和肠梗阻。此外，还为在管理这些患者方面缺乏丰富经验的医生提供了一种针对年长囊性纤维化患者进行临床评估、随访及治疗的实用方法。文中还讨论了目前在识别囊性纤维化基因、基本缺陷以及心肺移植应用方面的研究。
