Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Yonsei University Graduate School, Seoul, South Korea.
PLoS One. 2020 Nov 23;15(11):e0242130. doi: 10.1371/journal.pone.0242130. eCollection 2020.
Comparing to data in patients with severe coronavirus diseases 2019 (COVID-19), there are few studies on the prevalence anxiety and/or depression in patients with asymptomatic or mildly symptomatic COVID-19. We investigated the clinical characteristics and the prevalence of anxiety and/or depression among asymptomatic or mildly symptomatic patients with COVID-19 and monitored their mental health using an online assessment. An online survey for monitoring and assessing the mental health of patients with COVID-19 using a mobile phone was conducted. We used the Hospital Anxiety and Depression Scale to measure anxiety and/or depression levels. Of the 234 patients, 66 patients were asymptomatic (28.2%), while the remaining 168 patients were mildly symptomatic. The prevalence of anosmia (p = 0.001) and ageusia (p = 0.008) significantly decreased with the increasing age. In addition, 19.8% and 14.0% patients had anxiety and/or depression in the first survey, and one week after the first survey, respectively. Compared to patients without anxiety and/or depression, those with anxiety and/or depression had a longer quarantine duration. We found that anomia and ageusia were relatively common in the young age group. Furthermore, one-fifth asymptomatic or mildly symptomatic patients with COVID-19 had anxiety and/or depression.
与严重 2019 冠状病毒病（COVID-19）患者的数据相比，针对无症状或轻度症状 COVID-19 患者中焦虑和/或抑郁发生率的研究较少。我们调查了无症状或轻度症状 COVID-19 患者的临床特征以及焦虑和/或抑郁的发生率，并使用在线评估监测他们的心理健康状况。我们使用医院焦虑和抑郁量表（Hospital Anxiety and Depression Scale）来衡量焦虑和/或抑郁水平。在 234 名患者中，66 名患者无症状（28.2%），其余 168 名患者轻度症状。嗅觉丧失（p = 0.001）和味觉丧失（p = 0.008）的发生率随年龄增长而显著降低。此外，在第一次调查中，19.8%和 14.0%的患者分别有焦虑和/或抑郁，而在第一次调查一周后，这一比例分别为 19.8%和 14.0%。与没有焦虑和/或抑郁的患者相比，有焦虑和/或抑郁的患者隔离时间更长。我们发现发音困难和味觉丧失在年轻人群中较为常见。此外，五分之一的无症状或轻度症状 COVID-19 患者有焦虑和/或抑郁。
