Royal National Ear, Nose and Throat and Eastman Dental Hospitals, London, United Kingdom.
AbScent, 14 London Road, Andover, Hampshire, United Kingdom.
Rhinology. 2020 Jun 1;58(3):299-301. doi: 10.4193/Rhin20.114.
The amelioration of the current COVID pandemic relies on swift and efficient case finding as well as stringent social distancing measures. Current advice suggests that fever or new onset dry cough are the commonest presenting complaints.
We present a case report and case series as well as other evidence that there is an important fourth presenting syndrome, namely isolated sudden onset anosmia (ISOA), which should be considered highly suspicious for SARS-CoV-2.
A patient presenting with ISOA who went on to test positive for infection with COVID-19 and did not develop any further symptoms as well as a case series of similar patients although limited by the lack of reliable testing at the moment.
We posit the existence of a fourth common syndrome of COVID-19 infection: isolated sudden onset anosmia (ISOA) and urge the international community to consider this presentation in current management advice.
当前 COVID 大流行的改善依赖于快速有效的病例发现和严格的社交距离措施。目前的建议表明，发热或新发干咳是最常见的症状。
我们提出了一个病例报告和病例系列，以及其他证据表明存在一个重要的第四种表现综合征，即孤立性突发性嗅觉丧失（ISOA），这对于 SARS-CoV-2 感染应高度怀疑。
一名出现 ISOA 的患者随后检测出 COVID-19 感染呈阳性，且没有出现任何其他症状，以及一系列类似患者的病例，尽管目前由于缺乏可靠的检测而受到限制。
我们提出了 COVID-19 感染的第四种常见综合征的存在：孤立性突发性嗅觉丧失（ISOA），并敦促国际社会在当前的管理建议中考虑这种表现。
