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印度尼西亚东爪哇省非住院无症状和轻症 COVID-19 患者中抑郁、焦虑和压力的流行情况及危险因素。

Prevalence of and risk factors for depression, anxiety, and stress in non-hospitalized asymptomatic and mild COVID-19 patients in East Java province, Indonesia.

机构信息

Indrapura Emergency Field Hospital, Surabaya, Indonesia.

Department of Internal Medicine, Faculty of Medicine Universitas Airlangga-Dr. Soetomo General Hospital, Surabaya, Indonesia.

出版信息

PLoS One. 2022 Jul 7;17(7):e0270966. doi: 10.1371/journal.pone.0270966. eCollection 2022.

DOI:10.1371/journal.pone.0270966
PMID:35797394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9262201/
Abstract

BACKGROUND

Despite abundant data on mental health during the COVID-19 pandemic, 3 important knowledge gaps continue to exist, i.e., 1) studies from low-/middle income countries (LMICs); 2) studies in the later period of the COVID-19 pandemic; and 3) studies on non-hospitalized asymptomatic and mild COVID-19 patients. To address the knowledge gaps, we assessed the prevalence of and the risk factors for mental health symptoms among non-hospitalized asymptomatic and mild COVID-19 patients in one LMIC (Indonesia) during the later period of the pandemic.

METHODS

This cross-sectional study was conducted in September 2020 in East Java province, Indonesia. Study population consisted of non-hospitalized asymptomatic and mild COVID-19 patients who were diagnosed based on reverse transcriptase-polymerase chain reaction results from nasopharyngeal swab. Mental health symptoms were evaluated using the Depression Anxiety Stress Scale-21.

RESULTS

From 778 non-hospitalized asymptomatic and mild COVID-19 patients, 608 patients were included in the analysis. Patients' median age was 35 years old and 61.2% were male. Of these, 22 (3.6%) reported symptoms of depression, 87 (14.3%) reported symptoms of anxiety, and 48 (7.9%) reported symptoms of stress. Multivariate logistic regression analysis showed that females were more likely to report symptoms of stress (adjusted odds ratio (aOR) = 1.98, p-value = 0.028); healthcare workers were more likely to report symptoms of depression and anxiety (aOR = 5.57, p-value = 0.002 and aOR = 2.92, p-value = 0.014, respectively); and those with a recent history of self-quarantine were more likely to report symptoms of depression and stress (aOR 5.18, p = 0.004 and aOR = 1.86, p = 0.047, respectively).

CONCLUSION

The reported prevalence of mental health symptoms, especially depression, was relatively low among non-hospitalized asymptomatic and mild COVID-19 patients during the later period of the COVID-19 pandemic in East Java province, Indonesia. In addition, several risk factors have been identified.

摘要

背景

尽管有大量关于 COVID-19 大流行期间心理健康的资料,但仍存在 3 个重要的知识空白,即 1)来自低收入和中等收入国家(LMICs)的研究;2)在 COVID-19 大流行后期的研究;3)对非住院无症状和轻症 COVID-19 患者的研究。为了解决这些知识空白,我们评估了在大流行后期,印度尼西亚一个低收入和中等收入国家(LMICs)中,非住院无症状和轻症 COVID-19 患者的心理健康症状的患病率和危险因素。

方法

这是一项横断面研究,于 2020 年 9 月在印度尼西亚东爪哇省进行。研究人群由根据鼻咽拭子逆转录-聚合酶链反应结果诊断为非住院无症状和轻症 COVID-19 的患者组成。使用抑郁焦虑压力量表-21 评估心理健康症状。

结果

在 778 名非住院无症状和轻症 COVID-19 患者中,有 608 名患者纳入分析。患者的中位年龄为 35 岁,61.2%为男性。其中,22 名(3.6%)报告有抑郁症状,87 名(14.3%)报告有焦虑症状,48 名(7.9%)报告有压力症状。多变量逻辑回归分析显示,女性更有可能报告有压力症状(调整后的优势比(aOR)=1.98,p 值=0.028);医务人员更有可能报告有抑郁和焦虑症状(aOR=5.57,p 值=0.002 和 aOR=2.92,p 值=0.014);最近有自我隔离史的人更有可能报告有抑郁和压力症状(aOR=5.18,p=0.004 和 aOR=1.86,p=0.047)。

结论

在印度尼西亚东爪哇省 COVID-19 大流行后期,非住院无症状和轻症 COVID-19 患者报告的心理健康症状(特别是抑郁)的患病率相对较低。此外,还确定了一些危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d5d/9262201/6ab3bf24e7bf/pone.0270966.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d5d/9262201/6ab3bf24e7bf/pone.0270966.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d5d/9262201/6ab3bf24e7bf/pone.0270966.g001.jpg

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