Biomedical Science Programme, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia.
Center for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia.
Syst Rev. 2020 Nov 23;9(1):265. doi: 10.1186/s13643-020-01517-0.
The prevalence of type-2 diabetes mellitus (T2DM) has been increasing globally. Without proper management, T2DM can develop into serious complications and even death. Diet modification is one of the most effective tools in managing T2DM at the early stage, but it requires knowledge and compliance from the patients. Thus, meal replacement (MR) has gained its popularity as a tool for diet modification to improve glycemic control and also reducing weight in T2DM patients. There are several existing meal replacement studies but not much is known on the general scope and effect of these existing MRs. Hence, this review is aimed to provide an overview of the existing evidences regarding the application of meal replacement on T2DM patients and identify the gaps or limitations in the studies.
The scoping review will be carried out in six stages: (1) identifying the research question, (2) identifying relevant studies through electronic databases (i.e., PubMed, Scopus, Cochrane Reviews, Google Scholar, EBSCOHOST, Science Direct) and also gray literature, and (3) selection of studies to be included based on inclusion criteria. Search and initial screening of studies to be included will be conducted by two independent reviewers. Discrepancies will then be solved through discussion with other reviewers; (4) charting and categorizing extracted data in a pretested data extraction form; (5) collating, summarizing, and reporting the results; and lastly, (6) conducting consultation with stakeholders and experts in diabetes.
This scoping review protocol is aimed to provide a framework enabling us to map and summarize the findings from existing studies involving meal replacement. It will help researchers to identify the research gap and provide recommendations for future meal replacement studies. The results from this scoping review will be useful to various stakeholders in healthcare. It is also part of a research project in which the information obtained will be utilized in a clinical trial of a developed meal replacement plan. Dissemination of knowledge will also be done through presentations at related scientific conferences.
全球范围内 2 型糖尿病（T2DM）的患病率一直在上升。如果没有适当的管理，T2DM 可能会发展成严重的并发症，甚至死亡。饮食调整是管理 T2DM 的最有效工具之一，但需要患者了解并遵守。因此，代餐已作为一种饮食调整工具而广受欢迎，以改善血糖控制并减轻 T2DM 患者的体重。有几项现有的代餐研究，但对于这些现有的代餐的一般范围和效果知之甚少。因此，本综述旨在提供关于代餐在 T2DM 患者中应用的现有证据概述，并确定研究中的差距或局限性。
该范围综述将分六个阶段进行：（1）确定研究问题；（2）通过电子数据库（即 PubMed、Scopus、Cochrane Reviews、Google Scholar、EBSCOHOST、Science Direct）和灰色文献确定相关研究；（3）根据纳入标准选择要纳入的研究。将由两名独立审查员进行研究的搜索和初步筛选。如果出现分歧，将通过与其他审查员讨论来解决；（4）使用经过预测试的数据提取表对提取的数据进行图表和分类；（5）整理、总结和报告结果；最后，（6）与糖尿病领域的利益相关者和专家进行咨询。
本范围综述方案旨在提供一个框架，使我们能够对涉及代餐的现有研究的结果进行映射和总结。它将帮助研究人员确定研究差距，并为未来的代餐研究提供建议。本范围综述的结果将对医疗保健领域的各种利益相关者有用。它也是一个研究项目的一部分，其中获得的信息将用于开发的代餐计划的临床试验。知识的传播也将通过在相关科学会议上的演示来进行。
