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家族性巨大肥厚性胃炎(梅内特里耶病)。

Familial giant hypertrophic gastritis (Ménétrier's disease).

作者信息

Larsen B, Tarp U, Kristensen E

机构信息

Medical Department, Silkeborg Hospital, Denmark.

出版信息

Gut. 1987 Nov;28(11):1517-21. doi: 10.1136/gut.28.11.1517.

DOI:10.1136/gut.28.11.1517
PMID:3322957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1433692/
Abstract

Familial giant hypertrophic gastritis involving three generations is reported. A review of the literature, where approximately 200 cases are described, showed only few cases of familial occurrence of this disease, and only in siblings. Our findings suggest dominant heredity, but considering the sparsity of familial occurrence reported earlier, heredity seems to be of only minor pathogenetic significance.

摘要

本文报道了累及三代人的家族性巨大肥厚性胃炎。文献综述显示,约200例相关病例中,仅有少数家族性发病的病例,且仅见于兄弟姐妹之间。我们的研究结果提示为显性遗传,但鉴于此前报道的家族性发病情况稀少,遗传因素在发病机制中的意义似乎较小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/93c4f6cb73e7/gut00249-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/1448d2c55e05/gut00249-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/ad16f5f8ee29/gut00249-0126-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/483ab220518b/gut00249-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/bfbd53d1f830/gut00249-0127-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/93c4f6cb73e7/gut00249-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/1448d2c55e05/gut00249-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/ad16f5f8ee29/gut00249-0126-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/483ab220518b/gut00249-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/bfbd53d1f830/gut00249-0127-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/1433692/93c4f6cb73e7/gut00249-0128-a.jpg

相似文献

1
Familial giant hypertrophic gastritis (Ménétrier's disease).家族性巨大肥厚性胃炎(梅内特里耶病)。
Gut. 1987 Nov;28(11):1517-21. doi: 10.1136/gut.28.11.1517.
2
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[Ménétrier's disease (review of the literature)].[梅内特里耶病(文献综述)]
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Ménétrièr's disease and idiopathic hypertrophic gastropathy.梅内特里耶病和特发性肥厚性胃病。
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[Ménétriér's disease in children].[儿童梅内特里耶病]
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Eur J Clin Invest. 1996 Dec;26(12):1156-9. doi: 10.1046/j.1365-2362.1996.530611.x.
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[Menetrier's disease. A rare, unrecognized illness].[梅内特里耶病。一种罕见的、未被认识的疾病]
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Gut. 1991 Dec;32(12):1565-7. doi: 10.1136/gut.32.12.1565.

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World J Gastroenterol. 2025 Aug 28;31(32):108401. doi: 10.3748/wjg.v31.i32.108401.
2
Giant Gastric Folds in Juvenile Polyposis.幼年性息肉病中的巨大胃皱襞
Case Rep Gastroenterol. 2021 Dec 23;15(3):985-993. doi: 10.1159/000521125. eCollection 2021 Sep-Dec.
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Hypertrophic gastropathy associated with gastric sarcoma in a dog.犬肥厚性胃病与胃肉瘤相关。

本文引用的文献

1
Chronic hypertrophic gastritis. Report of two cases in siblings.慢性肥厚性胃炎。一对同胞兄妹病例报告。
Am J Gastroenterol. 1962 May;37:525-36.
2
Giant hypertrophy of the gastric mucosa, hypoproteinemia and edema (Menetrier's disease).胃黏膜巨大肥厚、低蛋白血症和水肿(梅内特里耶病)。
Am J Med. 1959 Jul;27(1):125-31. doi: 10.1016/0002-9343(59)90066-x.
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The mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa.与胃黏膜巨大肥厚相关的低蛋白血症机制。
J Vet Diagn Invest. 2021 Jan;33(1):112-115. doi: 10.1177/1040638720966972. Epub 2020 Oct 22.
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Unusual case of adult familial Menetrier disease in siblings.成人兄弟姐妹患家族性梅内特里耶病的罕见病例。
BMJ Case Rep. 2019 Oct 23;12(10):e231175. doi: 10.1136/bcr-2019-231175.
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Hedgehog signaling in the stomach.胃中的刺猬信号通路。
Curr Opin Pharmacol. 2016 Dec;31:76-82. doi: 10.1016/j.coph.2016.09.003. Epub 2016 Oct 14.
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Atypical Clinical and Diagnostic Features in Ménétrier's Disease in a Child.儿童胃黏膜巨肥厚症的非典型临床及诊断特征
Case Rep Gastrointest Med. 2011;2011:480610. doi: 10.1155/2011/480610. Epub 2011 Sep 21.
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The role of Sonic Hedgehog as a regulator of gastric function and differentiation.作为一种调节胃功能和分化的信号分子,Sonic Hedgehog 发挥着重要作用。
Vitam Horm. 2012;88:473-489. doi: 10.1016/B978-0-12-394622-5.00021-3.
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Ménétrier's disease of the stomach: a clinical challenge.胃的梅内特里耶病:一项临床挑战。
Curr Gastroenterol Rep. 2011 Dec;13(6):513-7. doi: 10.1007/s11894-011-0222-8.
9
Beyond gastritis and before cancer: the strange case of Ménétrier's disease.胃炎之后、癌症之前:胃黏膜巨肥厚症的奇特病例
Intern Emerg Med. 2011 Aug;6(4):369-71. doi: 10.1007/s11739-010-0471-9. Epub 2010 Oct 14.
10
Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells.Sonic hedgehog 表达缺失导致壁细胞丢失,引起胃泌素过度分泌和黏膜表面细胞过度增殖。
Gastroenterology. 2010 Feb;138(2):550-61, 561.e1-8. doi: 10.1053/j.gastro.2009.11.002. Epub 2009 Nov 10.
N Engl J Med. 1957 Nov 7;257(19):906-12. doi: 10.1056/NEJM195711072571902.
4
Precancerous conditions and epithelial dysplasia in the stomach.胃部的癌前病变和上皮发育异常
J Clin Pathol. 1980 Aug;33(8):711-21. doi: 10.1136/jcp.33.8.711.
5
Ménétrier's disease in children: report of a patient and review of sixteen other cases.儿童梅内特里耶病:1例报告并复习其他16例病例
Gastroenterology. 1981 May;80(5 pt 1):1042-7.
6
Menetrier's disease in childhood: report of two cases and a review of the literature.儿童梅内特里耶病:两例报告并文献复习
J Pediatr Surg. 1981 Oct;16(5):707-11. doi: 10.1016/s0022-3468(81)80557-x.
7
Pachydermoperiostosis, hypertrophic gastropathy, and peptic ulcer.厚皮性骨膜病、肥厚性胃病和消化性溃疡。
Gastroenterology. 1983 Apr;84(4):834-9.
8
Ménétrièr's disease and idiopathic hypertrophic gastropathy.梅内特里耶病和特发性肥厚性胃病。
Ann Intern Med. 1984 Apr;100(4):565-70. doi: 10.7326/0003-4819-100-4-565.
9
Thick gastric folds in childhood.儿童期胃黏膜皱襞增厚。
Am J Roentgenol Radium Ther Nucl Med. 1971 May;112(1):83-92. doi: 10.2214/ajr.112.1.83.
10
The clinical spectrum of hypertrophic hypersecretory gastropathy. Report of 50 patients.肥厚性高分泌性胃病的临床谱。50例患者的报告。
Gastrointest Endosc. 1971 Nov;18(2):69-73. doi: 10.1016/s0016-5107(71)74033-4.