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微型角膜刀辅助准分子激光原位角膜磨镶术后瓣片贴合不良:一例报告并文献复习

Non adherence of flap following microkeratome-assisted laser-assisted keratomileusis: A case report and review of literature.

作者信息

Sharma Ashok, Sharma Rajan

机构信息

Cornea Centre, Chandigarh, India.

出版信息

Indian J Ophthalmol. 2020 Dec;68(12):3045-3047. doi: 10.4103/ijo.IJO_1525_20.

DOI:10.4103/ijo.IJO_1525_20
PMID:33229701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7857003/
Abstract

A 28-year-old male underwent microkeratome assisted Laser-assisted in situ keratomileusis (LASIK) for, myopia. On postoperative day 1, patient had a large epithelial defect in OD. The corneal epithelial defect healed within 72 hours, but sub-optimal vision persisted. The patient was referred for further management to us. On evaluation, patient had non-healing of flap margin at 5 o'clock. Fluoroscein stain revealed no corneal epithelial defect, but a large pool of dye beneath the LASIK flap. A clinical diagnosis of non-adherence of LASIK flap was considered. Application of bandage contact lens was done. LASIK flap completely healed in 1 week. Possible etiologies are discussed and literature is reviewed.

摘要

一名28岁男性接受了微型角膜刀辅助的准分子激光原位角膜磨镶术(LASIK)治疗近视。术后第1天,患者右眼出现大片上皮缺损。角膜上皮缺损在72小时内愈合,但视力仍未达到最佳状态。该患者被转诊至我们处进行进一步治疗。经评估,患者5点处的角膜瓣边缘未愈合。荧光素染色显示角膜上皮无缺损,但在LASIK角膜瓣下有一大片染料积聚。考虑临床诊断为LASIK角膜瓣贴合不良。应用了绷带式隐形眼镜。LASIK角膜瓣在1周内完全愈合。讨论了可能的病因并回顾了相关文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/7857003/dc76916ee934/IJO-68-3045-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/7857003/dc76916ee934/IJO-68-3045-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/7857003/dc76916ee934/IJO-68-3045-g001.jpg

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本文引用的文献

1
Microcapillary sign of flap alignment in femtosecond laser-assisted in situ keratomileusis.飞秒激光原位角膜磨镶术中瓣对齐的微毛细血管征
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Early wound healing of laser in situ keratomileusis-like flaps after treatment with human corneal stromal stem cells.人角膜基质干细胞治疗后准分子原位角膜磨镶术样瓣的早期伤口愈合
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Delineation of LASIK flaps with prednisolone acetate eyedrops.
用醋酸泼尼松龙滴眼液描绘准分子激光原位角膜磨镶术(LASIK)角膜瓣。
J Ophthalmic Vis Res. 2014 Jan;9(1):116-8.
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Intraoperative and early postoperative flap-related complications of laser in situ keratomileusis using two types of Moria microkeratomes.
Int Ophthalmol. 2014 Oct;34(5):1107-14. doi: 10.1007/s10792-014-9919-7. Epub 2014 Feb 17.
5
Adhesion of laser in situ keratomileusis-like flaps in the cornea: Effects of crosslinking, stromal fibroblasts, and cytokine treatment.角膜激光原位磨镶样瓣的黏附:交联、基质成纤维细胞和细胞因子处理的影响。
J Cataract Refract Surg. 2011 Jan;37(1):166-72. doi: 10.1016/j.jcrs.2010.07.028.
6
Short-term effect of topical brimonidine tartrate on intrastromal corneal pressure in rabbits.兔眼巩膜间角膜内压的短期局部应用溴莫尼定效果。
J Refract Surg. 2010 Jul;26(7):533-5. doi: 10.3928/1081597X-20100310-01.
7
Comparison of flap adhesion strength using the Amadeus microkeratome and the IntraLase iFS femtosecond laser in rabbits.使用阿玛迪斯微型角膜刀和IntraLase iFS飞秒激光对兔角膜瓣黏附强度的比较。
J Refract Surg. 2008 Nov;24(9):875-8. doi: 10.3928/1081597X-20081101-04.
8
Stability of the laser in situ keratomileusis corneal flap in rabbit eyes.兔眼准分子原位角膜磨镶术角膜瓣的稳定性
J Cataract Refract Surg. 2006 Jun;32(6):1046-51. doi: 10.1016/j.jcrs.2006.02.038.
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