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在临床实验室中解读痰液质量的随机试验。

Randomized trial interpreting sputum quality in a clinical laboratory.

作者信息

Mizrachi H H, Valenstein P N

机构信息

Department of Pathology, State University of New York, Stony Brook 11794-8691.

出版信息

J Clin Microbiol. 1987 Dec;25(12):2327-9. doi: 10.1128/jcm.25.12.2327-2329.1987.

DOI:10.1128/jcm.25.12.2327-2329.1987
PMID:3323227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC269481/
Abstract

The role for laboratory interpretation of microbiologic results remains controversial, and many laboratories leave the interpretation of culture results entirely to physicians. We examined the effects of furnishing a laboratory interpretation of sputum quality on physician decision making. Quality of sputum was determined on Gram-stained smears by using a modification of the criteria of Bartlett (R. C. Bartlett, Medical Microbiology: Quality, Cost, and Clinical Relevance, p. 24-31, 1974). A total of 301 poor-quality specimens were randomized either to receive written interpretation of Gram stain results or to a control group for which Gram stain results were reported without interpretation. Physicians were more likely to follow up a poor-quality specimen with a second specimen if they had been furnished an interpretation of the results from the original Gram stain (22 versus 12%; P = 0.025). We conclude that laboratory-based interpretation of microbiologic results can improve physician decision making.

摘要

实验室对微生物学检测结果的解读作用仍存在争议,许多实验室将培养结果的解读完全交给医生。我们研究了提供痰液质量的实验室解读对医生决策的影响。通过对Bartlett标准(R.C.Bartlett,《医学微生物学:质量、成本和临床相关性》,第24 - 31页,1974年)进行修改,在革兰氏染色涂片上确定痰液质量。总共301份质量不佳的标本被随机分为两组,一组接受革兰氏染色结果的书面解读,另一组为对照组,报告革兰氏染色结果但无解读。如果医生得到了原始革兰氏染色结果的解读,他们更有可能对质量不佳的标本进行第二次采样(22%对12%;P = 0.025)。我们得出结论,基于实验室的微生物学检测结果解读可以改善医生的决策。

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本文引用的文献

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Bacteriology of the lower respiratory tract in health and chronic diseases.健康与慢性疾病状态下的下呼吸道细菌学
N Engl J Med. 1958 Jan 9;258(2):71-4. doi: 10.1056/NEJM195801092580204.
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Etiological diagnosis of bacterial pneumonia by gram stain and quantitative culture of expectorates. Leukocytes or alveolar macrophages as indicators of sample representativity.通过痰液革兰氏染色和定量培养进行细菌性肺炎的病因诊断。以白细胞或肺泡巨噬细胞作为样本代表性的指标。
Scand J Infect Dis. 1983;15(2):153-60. doi: 10.3109/inf.1983.15.issue-2.05.
7
A plea for clinical relevance in medical microbiology.对医学微生物学临床相关性的呼吁。
Am J Clin Pathol. 1974 Jun;61(6):867-72. doi: 10.1093/ajcp/61.6.867.
8
The nonvalue of sputum culture in the diagnosis of pneumococcal pneumonia.痰培养在肺炎球菌肺炎诊断中的无价值性。
Am Rev Respir Dis. 1971 Jun;103(6):845-8. doi: 10.1164/arrd.1971.103.6.845.
9
Clinical value of paired sputum and transtracheal aspirates in the initial management of pneumonia.痰液与经气管抽吸物配对在肺炎初始治疗中的临床价值
Chest. 1985 May;87(5):631-5. doi: 10.1378/chest.87.5.631.
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