Department of Chemical & Biomolecular Engineering, Sogang University, 35 Baekbeom-Ro, Mapo-Gu, Seoul 04107, Korea.
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Biosensors (Basel). 2020 Nov 20;10(11):185. doi: 10.3390/bios10110185.
The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop biosensors for achieving high sensitivity and selectivity. Among the latest nanomaterials attracting attention, MXene is one of the best materials for the development of biosensors because of its various superior properties. MXenes are two-dimensional inorganic compounds with few atomic layers that possess excellent characteristics including high conductivity and superior fluorescent, optical, and plasmonic properties. In this review, advanced biosensors developed on the basis of the MXene nanocomposite are discussed with the selective overview of recently reported studies. For this, introduction of the MXene including the definition, synthesis methods, and its properties are discussed. Next, MXene-based electrochemical biosensors and MXene-based fluorescent/optical biosensors are provided, which are developed on the basis of the exceptional properties of the MXene nanocomposite. This review will suggest the direction for use of the Mxene nanocomposite to develop advanced biosensors with high sensitivity and selectivity.
开发具有高灵敏度和选择性的先进生物传感器是生物传感器领域最受关注的问题之一。为了满足这一要求，迄今为止，已经引入了许多纳米材料来开发生物传感器，以实现高灵敏度和选择性。在最新引起关注的纳米材料中，MXene 是用于开发生物传感器的最佳材料之一，因为它具有多种优越的性能。MXenes 是具有少数原子层的二维无机化合物，具有出色的特性，包括高导电性和卓越的荧光、光学和等离子体特性。在这篇综述中，讨论了基于 MXene 纳米复合材料开发的先进生物传感器，并选择性地综述了最近报道的研究。为此，讨论了 MXene 的介绍，包括定义、合成方法及其性质。接下来，提供了基于 MXene 的电化学生物传感器和基于 MXene 的荧光/光学生物传感器，它们是基于 MXene 纳米复合材料的特殊性质开发的。这篇综述将为使用 MXene 纳米复合材料开发具有高灵敏度和选择性的先进生物传感器提供方向。
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