Odom Gage C, Cottler Linda B, Striley Catherine W, Lopez-Quintero Catalina
Department of Epidemiology, University of Florida, Gainesville, FL 32611, USA.
Int J Womens Health. 2020 Nov 16;12:1075-1088. doi: 10.2147/IJWH.S266540. eCollection 2020.
While accumulated evidence has shown that the prevalence of cannabis use among pregnant women in the US has increased in recent years, little is known about the specific subpopulations affected. The aim of this study was to estimate the prevalence and correlates of the perceived risk of weekly cannabis use, past 30-day cannabis use, and frequency of past 30-day cannabis use among US pregnant women.
We analyzed data from 2,247 pregnant women 14 to 44 years of age surveyed in the 2015 to 2017 cross-sectional National Survey on Drug Use and Health. Analyses account for the sampling design. Primary outcomes included perceived risk of weekly cannabis use, past 30-day cannabis use, and frequency of cannabis use. We conducted multivariable logistic and negative binomial regression models to assess the associations between the primary outcomes and multiple correlates.
Among US pregnant women, 21.6% (95% CI=19.4, 23.8) did not perceive any risk associated with weekly cannabis use, 5.3% (95% CI=4.2, 6.5) used cannabis in the past 30 days, and among past-month users, the average number of days of use was 15.6 (95% CI=13.5, 17.7). Pregnant women living below the poverty line were both more likely to perceive no risk of weekly cannabis use (aOR=1.8; 95% CI=1.3, 2.5) and use cannabis more often in the past 30 days (aOR=2.9; 95% CI=1.5, 5.7) than pregnant women within an income bracket of more than two times the federal poverty threshold. Age, race, trimester of pregnancy, co-use of tobacco and/or alcohol were also associated with these outcomes.
Younger age, living in poverty, early trimester of pregnancy, and co-use of tobacco and/or alcohol increased the odds of cannabis use among pregnant women. As cannabis legalization spreads and cannabis use is increasingly perceived as safe, there is a growing need for research to determine the reasons why women in the identified at-risk subgroups are using cannabis during pregnancy.
虽然越来越多的证据表明,近年来美国孕妇中使用大麻的比例有所上升,但对于受影响的具体亚人群知之甚少。本研究的目的是估计美国孕妇中每周使用大麻的感知风险、过去30天内使用大麻的情况以及过去30天内使用大麻的频率,并分析其相关因素。
我们分析了2015年至2017年全国药物使用和健康横断面调查中对2247名年龄在14至44岁之间的孕妇进行调查的数据。分析考虑了抽样设计。主要结果包括每周使用大麻的感知风险、过去30天内使用大麻的情况以及大麻使用频率。我们进行了多变量逻辑回归和负二项回归模型,以评估主要结果与多个相关因素之间的关联。
在美国孕妇中,21.6%(95%可信区间=19.4, 23.8)认为每周使用大麻没有任何风险,5.3%(95%可信区间=4.2, 6.5)在过去30天内使用过大麻,在过去一个月的使用者中,平均使用天数为15.6天(95%可信区间=13.5, 17.7)。生活在贫困线以下的孕妇比收入超过联邦贫困线两倍的孕妇更有可能认为每周使用大麻没有风险(调整后的比值比=1.8;95%可信区间=1.3, 2.5),并且在过去30天内更频繁地使用大麻(调整后的比值比=2.9;95%可信区间=1.5, 5.7)。年龄、种族、孕期、同时使用烟草和/或酒精也与这些结果相关。
年龄较小、生活贫困、孕早期以及同时使用烟草和/或酒精会增加孕妇使用大麻的几率。随着大麻合法化的蔓延,大麻使用越来越被视为安全,越来越需要进行研究以确定已确定的高危亚组中的女性在怀孕期间使用大麻的原因。