Neill W A, Ritzmann L W, Okies J E, Anderson R P, Selden R
Cardiovasc Clin. 1977;8(2):179-87.
Forty-two patients with acute coronary insufficiency (high risk subgroup) were randomly assigned to urgent coronary bypass surgery or to initial medical therapy followed by elective coronary bypass at four months if indicated at that time for relief of incapacitation angina pectoris. Coronary bypass performed on an urgent basis offered no advantage in preventing early myocardial infarction or death. The acute illness was resolved without permanent complications in most patients by either urgent bypass surgery or intensive medical therapy. The functional capacity at four months as assessed by objective testing was much greater in the urgent surgical group. Elective bypass surgery was carried out at that point in about half of the medical patients due to persistent incapacitating angina. Later serious complications have continued to occur in the medical patients but have not occurred up to the present time in the urgent surgical patients.
42例急性冠状动脉功能不全患者（高危亚组）被随机分为两组，一组接受紧急冠状动脉搭桥手术，另一组先接受初始药物治疗，若四个月时因失能性心绞痛需要缓解则接受择期冠状动脉搭桥手术。紧急进行冠状动脉搭桥手术在预防早期心肌梗死或死亡方面并无优势。多数患者通过紧急搭桥手术或强化药物治疗，急性疾病得到解决且无永久性并发症。通过客观测试评估，四个月时紧急手术组的功能能力要强得多。约一半接受药物治疗的患者因持续性失能性心绞痛在此时接受了择期搭桥手术。后来，接受药物治疗的患者持续出现严重并发症，但紧急手术患者至今未出现此类情况。
