Loughborough University, Epinal Way, Loughborough LE11 3TU, United Kingdom.
Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, United Kingdom.
Diabetes Res Clin Pract. 2021 Jan;171:108554. doi: 10.1016/j.diabres.2020.108554. Epub 2020 Nov 22.
We describe the advantages and diagnostic/prognostic significance of low-field, near-portable benchtop NMR spectrometers for the multicomponent metabolomics analysis of targeted and untargeted urinary biomarkers (≥15) in type 2 diabetes patients. Implementation of these facilities at 'point-of-care' clinical sites may yield valuable advantages for the sequential monitoring of diabetic and prediabetic individuals.
我们描述了低场、近便携式台式 NMR 光谱仪在 2 型糖尿病患者靶向和非靶向尿生物标志物(≥15)的多组分代谢组学分析中的优势,以及其诊断/预后意义。在“床边”临床点实施这些设施可能为糖尿病和糖尿病前期个体的连续监测带来有价值的优势。