Sun Q M, Qin Q S, Chen B X, Shao R F, Zhang J S, Li Y
Sleep Medicine Center, Shantou University Medical College, Shantou 515041, China.
Laboratory of Human Virology and Oncology, Shantou University Medical College, Shantou 515041, China.
Zhonghua Yi Xue Za Zhi. 2020 Nov 24;100(43):3419-3424. doi: 10.3760/cma.j.cn112137-20200302-00557.
To investigate the severity of stress, anxiety, depression and insomnia during the novel coronavirus disease (COVID-19) pandemic in adults outside Hubei Province, China. An online survey of psychological and sleep by using Questionnaire Star program from 5th to 19th February 2020 was conducted. The Impact of Event Scale-Revised was used to assess COVID-19 outbreak-related stress symptoms. Meanwhile, Questionnaires of Generalized Anxiety Disorder-7, Patient Health Questionnaire-9 and the Insomnia Severity Index were respectively used to assess the severity of anxiety, depression and insomnia symptoms prior to and during the COVID-19 pandemic. A total of 3 134 subjects were included. Among the included subjects, 15.5% (487), 24.9% (779), 28.7% (899) and 30.9% (968) of the subjects had COVID-19-related stress symptoms, anxiety, depression and insomnia after the COVID-19 outbreak, respectively. The severity levels of anxiety, depression and insomnia were significantly increased during the COVID-19 pandemic compared to prior to the outbreak (all <0.01). Furthermore, the subjects' stress response to the COVID-19 outbreak was an independent risk factor for increased anxiety, depression and insomnia after the outbreak. The COVID-19 outbreak resulted in related stress response and widespread increase in anxiety, depression, and insomnia outside Hubei Province, China in the general population. The aggravation of anxiety, depression and insomnia is associated with stress levels. Our data demonstrate that the widespread psychological and insomnia problems in the general population need to be addressed at the early phase of the pandemic.
为调查中国湖北省以外成年人在新型冠状病毒肺炎（COVID-19）大流行期间的压力、焦虑、抑郁和失眠的严重程度。于2020年2月5日至19日使用问卷星程序进行了一项关于心理和睡眠的在线调查。采用事件影响量表修订版评估与COVID-19疫情相关的压力症状。同时，分别使用广泛性焦虑障碍7项问卷、患者健康问卷9项和失眠严重程度指数评估COVID-19大流行之前和期间焦虑、抑郁和失眠症状的严重程度。共纳入3134名受试者。在纳入的受试者中，分别有15.5%（487名）、24.9%（779名）、28.7%（899名）和30.9%（968名）的受试者在COVID-19疫情后出现了与COVID-19相关的压力症状、焦虑、抑郁和失眠。与疫情爆发前相比，COVID-19大流行期间焦虑、抑郁和失眠的严重程度显著增加（均P<0.01）。此外，受试者对COVID-19疫情的应激反应是疫情后焦虑、抑郁和失眠增加的独立危险因素。COVID-19疫情导致中国湖北省以外普通人群出现相关应激反应以及焦虑、抑郁和失眠的普遍增加。焦虑、抑郁和失眠的加重与压力水平相关。我们的数据表明，普通人群中广泛存在的心理和失眠问题需要在大流行的早期阶段得到解决。
