Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Computational Biology, Ingolstädter Landstr. 1, D-85764, Neuherberg, Germany.
Hayashi Children's Clinic, 4-6-11-1F Nagata, Joto-ku Osaka-Shi, Osaka, 536-0022, Japan.
Environ Health. 2020 Nov 25;19(1):123. doi: 10.1186/s12940-020-00661-3.
We thank Sani Rachman Soleman et al. for three specific points of criticism concerning our investigation of the ecological association between low birth weight (LBW) and radioactive contamination in Japan after the Fukushima Daiichi Nuclear Power Plant (FDNPP) accidents: 1. Ecological variables are not justified enough to adjust potential confounding. 2. The spatiotemporal regression model does not consider temporal reduction in radiation dose rate. 3. Dose-response plot between dose rates and odds ratios overestimates R and underestimates p-value. This criticism is a good starting point to explain some of the technical backgrounds of our approach in more detail.
我们感谢 Sani Rachman Soleman 等人对我们关于福岛第一核电站（FDNPP）事故后日本低出生体重（LBW）与放射性污染之间的生态关联的研究提出的三点具体批评：1. 生态变量不足以调整潜在的混杂因素。2. 时空回归模型没有考虑辐射剂量率的时间减少。3. 剂量率与优势比之间的剂量反应图高估了 R 值，低估了 p 值。这一批评为详细解释我们方法的一些技术背景提供了一个良好的起点。
