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伪装成肝脓肿的胆囊癌肉瘤

Gallbladder carcinosarcoma masquerading as a hepatic abscess.

作者信息

Khurram Ruhaid, Khamar Rahul, Lunat Raees, Novelli Daniel, Ozretić Luka, Chaudhary Khurram

机构信息

Royal Free Hospital, Royal Free London NHS Foundation Trust, Pond St, Hampstead, London NW3 2QG, UK.

出版信息

Radiol Case Rep. 2020 Nov 12;16(1):152-156. doi: 10.1016/j.radcr.2020.10.058. eCollection 2021 Jan.

DOI:10.1016/j.radcr.2020.10.058
PMID:33240458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7674158/
Abstract

Carcinosarcomas of the gallbladder are extremely rare tumors and infrequently reported in the literature. We demonstrate a case of a 64-year-old female who presented with a 2-month history of a right upper quadrant mass, intermittent fevers, and abdominal distension following recent travel to Ghana. A computed tomography (CT) scan of the abdomen and pelvis demonstrated a large hepatic lesion with co-existing gallbladder distension, suggestive of a hepatic abscess. The patient was initially managed with intravenous antibiotics but failed to respond to treatment. A subsequent magnetic resonance imaging (MRI) scan of the liver showed a locally invasive lobulated soft tissue lesion arising from the gallbladder fundus and extending into the liver parenchyma. The lesion was surgically excised with a central hepatectomy. Histopathologic analysis showed a carcinosarcoma of the gallbladder.

摘要

胆囊癌肉瘤是极其罕见的肿瘤,文献中鲜有报道。我们报告一例64岁女性病例,该患者在近期前往加纳旅行后出现右上腹肿块、间歇性发热和腹胀2个月。腹部和盆腔计算机断层扫描(CT)显示肝脏有一个大的病变,同时伴有胆囊扩张,提示肝脓肿。患者最初接受静脉抗生素治疗,但治疗无效。随后肝脏的磁共振成像(MRI)扫描显示,一个局部浸润的分叶状软组织病变起源于胆囊底部并延伸至肝实质。该病变通过中央肝切除术进行了手术切除。组织病理学分析显示为胆囊癌肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/771f05a31ac7/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/999af84b454d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/7f848730bc28/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/0b6e5d3137fd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/771f05a31ac7/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/999af84b454d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/7f848730bc28/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/0b6e5d3137fd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c2b/7674158/771f05a31ac7/gr4.jpg

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本文引用的文献

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Gallbladder Cancer in the 21st Century.21世纪的胆囊癌
J Oncol. 2015;2015:967472. doi: 10.1155/2015/967472. Epub 2015 Sep 1.
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Carcinosarcoma of the gallbladder: a case report and review of the literature.胆囊癌肉瘤:一例报告并文献复习
Int J Clin Exp Pathol. 2015 Jun 1;8(6):7464-9. eCollection 2015.
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Carcinosarcoma of the gallbladder: a case report and review of the literature.胆囊癌肉瘤:一例报告并文献复习
Gallbladder carcinosarcoma with a poor prognosis: A case report.
预后不良的胆囊癌肉瘤:一例报告
World J Clin Cases. 2024 Apr 6;12(10):1817-1823. doi: 10.12998/wjcc.v12.i10.1817.
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Highly Invasive Biliary Cancer Presenting as Multiple Extrabiliary Lesions Masquerading as Abscesses.表现为多个伪装成脓肿的肝外病变的高侵袭性胆管癌。
Cureus. 2023 Nov 16;15(11):e48894. doi: 10.7759/cureus.48894. eCollection 2023 Nov.
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Comparison of carcinosarcoma and adenocarcinoma of the gallbladder: a study based on SEER population for propensity matching and nomogram analysis.胆囊癌肉瘤与腺癌的比较:一项基于监测、流行病学和最终结果(SEER)数据库人群的倾向匹配和列线图分析研究
J Cancer Res Clin Oncol. 2023 Nov;149(15):13985-13993. doi: 10.1007/s00432-023-05220-0. Epub 2023 Aug 5.
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Carcinosarcoma of gallbladder: A world review.胆囊癌肉瘤:一项全球综述。
World J Clin Oncol. 2021 Dec 24;12(12):1244-1263. doi: 10.5306/wjco.v12.i12.1244.
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Gallbladder cancer of two histological origins: A case report and review of literature.两种组织学起源的胆囊癌:一例报告及文献复习
Int J Surg Case Rep. 2021 Apr;81:105704. doi: 10.1016/j.ijscr.2021.105704. Epub 2021 Mar 4.
J Clin Diagn Res. 2013 Mar;7(3):560-2. doi: 10.7860/JCDR/2013/4924.2825. Epub 2013 Mar 1.
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Gallbladder carcinosarcoma.胆囊癌肉瘤
BMJ Case Rep. 2011 Apr 1;2011:bcr0520103009. doi: 10.1136/bcr.05.2010.3009.
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Surgical outcome of carcinosarcoma of the gall bladder: a review.胆囊癌肉瘤的手术治疗效果:一项综述。
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Prognostic significance of race and tumor size in carcinosarcoma of gallbladder: a meta-analysis of 68 cases.种族和肿瘤大小在胆囊癌肉瘤中的预后意义:68例病例的荟萃分析
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