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采用椎间融合手术和U形腰椎棘突间撑开器的腰椎生物力学分析

Biomechanical analysis of lumbar spine with interbody fusion surgery and U-shaped lumbar interspinous spacers.

作者信息

Yin Jia-Yu, Guo Li-Xin

机构信息

School of Mechanical Engineering and Automation, Northeastern University, Shenyang, China.

出版信息

Comput Methods Biomech Biomed Engin. 2021 May;24(7):788-798. doi: 10.1080/10255842.2020.1851368. Epub 2020 Nov 26.

DOI:10.1080/10255842.2020.1851368
PMID:33241697
Abstract

Previous research indicates whole-body vibration may lead to low back pain. The aim of this study is assessing the dynamic characteristics of a lumbar spine with Coflex and Coflex-F (commercial implants used as lumbar interspinous spacers) and effect of lumbar interbody fusion surgery. A transient dynamic analysis is performed on three numerical lumbar spine models under the loading condition of a vertical sinusoidal force of ±40 N with a compressive follower preload of 400 N. Also, Coflex-F model with and without interbody fusion surgery is analyzed under the same loading condition. The results show that the maximum value and vibration amplitude of von Mises stress in annulus ground substance (AGS) and intradiscal pressure (IDP) at implanted segment decrease from healthy model to Coflex model, and Coflex-F model. By contrast, for adjacent segments the maximum value of implanted models are larger than that of healthy model. The maximum value of endplates with and without cage are 2.44 MPa and 1.73 MPa (L4 inferior endplate), 1.94 MPa and 1.42 MPa (L5 superior endplate), respectively. The vibration amplitude of Coflex-F model with fusion surgery is smaller than that without fusion surgery. Coflex and Coflex-F not only protect implanted segment but also have a negative effect on adjacent segments. Inserting cage for Coflex-F model can absorb vibration energy at adjacent segments.

摘要

先前的研究表明,全身振动可能会导致腰痛。本研究的目的是评估使用Coflex和Coflex-F(用作腰椎棘突间间隔器的商用植入物)时腰椎的动态特性以及腰椎椎间融合手术的效果。在±40 N的垂直正弦力和400 N的压缩随动预载的加载条件下,对三个数值腰椎模型进行瞬态动力学分析。此外,在相同的加载条件下,分析了进行和未进行椎间融合手术的Coflex-F模型。结果表明,从健康模型到Coflex模型以及Coflex-F模型,植入节段的髓核基质(AGS)中的冯·米塞斯应力和椎间盘内压力(IDP)的最大值和振动幅度均降低。相比之下,对于相邻节段,植入模型的最大值大于健康模型。有和没有椎间融合器的终板的最大值分别为2.44 MPa和1.73 MPa(L4下终板),1.94 MPa和1.42 MPa(L5上终板)。进行融合手术的Coflex-F模型的振动幅度小于未进行融合手术的模型。Coflex和Coflex-F不仅能保护植入节段,而且对相邻节段有负面影响。为Coflex-F模型插入椎间融合器可以吸收相邻节段的振动能量。

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Sci Rep. 2023 Oct 10;13(1):17116. doi: 10.1038/s41598-023-43399-x.
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Recent advancement in finite element analysis of spinal interbody cages: A review.
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