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本文引用的文献

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Psychological correlates of interest in genetic testing among Korean American adoptees and their parents.韩裔美国家庭收养子女及其父母对基因检测的兴趣的心理相关性。
J Genet Couns. 2020 Jun;29(3):460-470. doi: 10.1002/jgc4.1237. Epub 2020 Mar 3.
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Genetic ancestry testing among white nationalists: From identity repair to citizen science.白人至上主义者的基因血统检测:从身份修复到公民科学。
Soc Stud Sci. 2019 Oct;49(5):653-681. doi: 10.1177/0306312719861434. Epub 2019 Jul 2.
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Physician preparedness for big genomic data: a review of genomic medicine education initiatives in the United States.医生应对大型基因组数据的准备情况:美国基因组医学教育计划述评。
Hum Mol Genet. 2018 Aug 1;27(R2):R250-R258. doi: 10.1093/hmg/ddy170.
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False-positive results released by direct-to-consumer genetic tests highlight the importance of clinical confirmation testing for appropriate patient care.直接面向消费者的基因检测产生的假阳性结果强调了为适当的患者护理进行临床确认检测的重要性。
Genet Med. 2018 Dec;20(12):1515-1521. doi: 10.1038/gim.2018.38. Epub 2018 Mar 22.
5
Does Lack of "Genetic-Relative Family Health History" Represent a Potentially Avoidable Health Disparity for Adoptees?缺乏“遗传相关家族健康史”是否代表了收养儿童潜在可避免的健康差距?
Am J Bioeth. 2016 Dec;16(12):33-38. doi: 10.1080/15265161.2016.1240255.
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Inferring genetic ancestry: opportunities, challenges, and implications.推断遗传血统:机遇、挑战和影响。
Am J Hum Genet. 2010 May 14;86(5):661-73. doi: 10.1016/j.ajhg.2010.03.011.
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Bio science: genetic genealogy testing and the pursuit of African ancestry.生物科学:基因族谱检测与对非洲血统的追寻。
Soc Stud Sci. 2008 Oct;38(5):759-83. doi: 10.1177/0306312708091929.
8
Genetics. The science and business of genetic ancestry testing.遗传学。基因谱系检测的科学与业务。
Science. 2007 Oct 19;318(5849):399-400. doi: 10.1126/science.1150098.
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Ethical principles of psychologists and code of conduct.心理学家的伦理原则与行为准则。
Am Psychol. 2002 Dec;57(12):1060-73.
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Stages of change and decisional balance for 12 problem behaviors.12种问题行为的改变阶段与决策平衡
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临床诊疗中面向消费者的基因族谱检测:心理治疗案例视角

Direct-to-Consumer Genetic Ancestry Testing in Clinical Encounters: Perspectives From Psychotherapy Cases.

作者信息

Rubanovich Caryn Kseniya, Zhang Wendy, Bloss Cinnamon S

机构信息

San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, United States.

Center for Empathy and Technology, T Denny Sanford Institute for Empathy and Compassion, University of California San Diego, La Jolla, CA, United States.

出版信息

JMIR Ment Health. 2020 Nov 26;7(11):e23596. doi: 10.2196/23596.

DOI:10.2196/23596
PMID:33242016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7728525/
Abstract

Despite the fact that direct-to-consumer (DTC) genetic ancestry testing (GAT) has been available for two decades, there is a lack of evidence-based guidance for clinicians who may work with patients who raise the topic of DTC-GAT. Although DTC-GAT accounts for the majority of the DTC genetic testing marketplace, it has received less attention than health-related testing from scientific and clinical communities. Importantly, however, from our personal experience, patients have been raising the topic of DTC-GAT in clinical encounters, including psychotherapy sessions. In this viewpoint, we present two cases of patients seen by two of the authors to raise awareness of this issue. We describe the implications of DTC-GAT for patients and clinicians, offer recommendations, and suggest future directions.

摘要

尽管直接面向消费者(DTC)的基因谱系检测(GAT)已经存在了二十年,但对于可能会遇到患者提及DTC-GAT这一话题的临床医生而言,却缺乏基于证据的指导。虽然DTC-GAT在DTC基因检测市场中占据了大部分份额,但相较于健康相关检测,它受到科学和临床界的关注较少。然而,重要的是,根据我们的个人经验,患者在临床诊疗过程中,包括心理治疗环节,一直在提及DTC-GAT这一话题。在这一观点文章中,我们展示了两位作者所接诊的两例患者,以提高对这一问题的认识。我们描述了DTC-GAT对患者和临床医生的影响,提供了建议,并提出了未来的方向。