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Challenges of Interpreting Cytomegalovirus DNAemia and Its Potential Association With Chronic Lung Disease in Children and Adolescents With Perinatally Acquired Human Immunodeficiency Virus Infection.解读巨细胞病毒血症的挑战及其与围产期获得性人类免疫缺陷病毒感染的儿童和青少年慢性肺病的潜在关联
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Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial.阿奇霉素与安慰剂治疗儿童和青少年HIV相关慢性肺病（BREATHE试验）：一项随机对照试验的研究方案
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Human Immunodeficiency Virus-Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High-Resolution Computed Tomographic Findings.津巴布韦儿童和青少年人类免疫缺陷病毒相关慢性肺病：胸部 X 线和高分辨率计算机断层扫描结果。
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巨细胞病毒特异性免疫球蛋白 G 与撒哈拉以南非洲围生期人类免疫缺陷病毒感染的儿童和青少年的慢性肺部疾病有关。

Cytomegalovirus-Specific Immunoglobulin G Is Associated With Chronic Lung Disease in Children and Adolescents from Sub-Saharan Africa Living With Perinatal Human Immunodeficiency Virus.

机构信息

Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

The Arctic University of Norway, Tromsø, Norway.

出版信息

Clin Infect Dis. 2021 Jul 1;73(1):e264-e266. doi: 10.1093/cid/ciaa1757.

DOI:10.1093/cid/ciaa1757
PMID:33242076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8491836/
Abstract

In a cross-sectional study of 296 children and adolescents from Zimbabwe living with perinatal human immunodeficiency virus, individuals with the top tertile of cytomegalovirus-specific immunoglobulin G titer had an increased odds of chronic lung disease (odds ratio, 3.33; 95% confidence interval, 1.37-8.85; P = .010).

摘要

在一项针对津巴布韦 296 名围产期感染人类免疫缺陷病毒的儿童和青少年的横断面研究中，巨细胞病毒特异性免疫球蛋白 G 滴度处于最高三分位的个体发生慢性肺部疾病的几率增加（比值比，3.33；95%置信区间，1.37-8.85；P =.010）。