家庭急救方法在居家分娩产后出血管理中的安全性和可行性:巴基斯坦农村地区的干预前后研究。
The Safety and Feasibility of a Family First Aid Approach for the Management of Postpartum Hemorrhage in Home Births: A Pre-post Intervention Study in Rural Pakistan.
机构信息
Gynuity Health Projects, 220 East 42nd Street Suite 710, New York, NY, 10017, USA.
National Committee for Maternal and Neonatal Health, Karachi, Pakistan.
出版信息
Matern Child Health J. 2021 Jan;25(1):118-126. doi: 10.1007/s10995-020-03047-6. Epub 2020 Nov 26.
OBJECTIVE
To evaluate the safety and feasibility of a Family First Aid approach whereby women and their families are provided misoprostol in advance to manage postpartum hemorrhage (PPH) in home births.
METHODS
A 12-month prospective, pre-post intervention study was conducted from February 2017 to February 2018. Women in their second and third trimesters were enrolled at home visits. Participants and their families received educational materials and were counseled on how to diagnose excessive bleeding and the importance of seeking care at a facility if PPH occurs. In the intervention phase, participants were also given misoprostol and counselled on how to administer the four 200 mcg tablets for first aid in case of PPH. Participants were followed-up postpartum to collect data on use of misoprostol for Family First Aid at home deliveries (primary outcome) and record maternal and perinatal outcomes.
RESULTS
Of the 4008 participants enrolled, 97% were successfully followed-up postpartum. Half of the participants in each phase delivered at home. Among home deliveries, the odds of reporting PPH almost doubled among in the intervention phase (OR 1.98; CI 1.43, 2.76). Among those reporting PPH, women in the intervention phase were significantly more likely to have received PPH treatment (OR 10.49; CI 3.37, 32.71) and 90% administered the dose correctly. No maternal deaths, invasive procedures or surgery were reported in either phase after home deliveries.
CONCLUSIONS
The Family First Aid approach is a safe and feasible model of care that provides timely PPH treatment to women delivering at home in rural communities.
目的
评估“家庭急救”方法的安全性和可行性,即提前向妇女及其家庭提供米索前列醇,以在家中分娩时处理产后出血(PPH)。
方法
这是一项为期 12 个月的前瞻性、前后干预研究,于 2017 年 2 月至 2018 年 2 月进行。在家访中招募处于第二和第三个孕期的妇女。向参与者及其家属提供教育材料,并就如何诊断出血过多以及如果发生 PPH 时到医疗机构就诊的重要性进行咨询。在干预阶段,还向参与者提供米索前列醇,并就如何在发生 PPH 时使用四片 200mcg 片剂进行急救进行指导。在产后对参与者进行随访,以收集在家中分娩时使用米索前列醇进行家庭急救的数据(主要结局),并记录产妇和围产期结局。
结果
在 4008 名入组的参与者中,97%的人在产后成功随访。每个阶段各有一半的参与者在家中分娩。在家中分娩中,干预阶段报告 PPH 的几率几乎翻了一番(OR 1.98;95%CI 1.43, 2.76)。在报告 PPH 的妇女中,干预阶段的妇女更有可能接受 PPH 治疗(OR 10.49;95%CI 3.37, 32.71),并且 90%的人正确使用了剂量。在家中分娩后,在两个阶段均未报告产妇死亡、有创性操作或手术。
结论
“家庭急救”方法是一种安全且可行的护理模式,可为在农村社区家中分娩的妇女提供及时的 PPH 治疗。