系统发育分析揭示了密切相关的流行O1分离株在老挝、泰国和越南的传播情况。
Phylogenetic Analysis Revealed the Dissemination of Closely Related Epidemic O1 Isolates in Laos, Thailand, and Vietnam.
作者信息
Morita Masatomo, Okada Kazuhisa, Yamashiro Tetsu, Sekizuka Tsuyoshi, Roobthaisong Amonrattana, Wongboot Warawan, Chantaroj Siriporn, Tu Nguyen Dong, Xangsayarath Phonepadith, Sithivong Noikaseumsy, Noilath Khambai, Vongdouangchanh Arounnapha, Kuroda Makoto, Hamada Shigeyuki, Izumiya Hidemasa, Ohnssishi Makoto
机构信息
Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi, Thailand.
出版信息
Open Forum Infect Dis. 2020 Oct 16;7(11):ofaa492. doi: 10.1093/ofid/ofaa492. eCollection 2020 Nov.
We performed whole-genome sequencing of O1 isolates from Laos, Thailand, and Vietnam, where cholera outbreaks occurred, to determine their genetic lineages. Core genome phylogenetic analysis revealed that the isolates located in same lineage without regional clusters, which suggests that closely related strains circulated in Southeast Asia.
我们对来自老挝、泰国和越南（霍乱暴发地区）的O1分离株进行了全基因组测序，以确定它们的遗传谱系。核心基因组系统发育分析显示，这些分离株位于同一谱系，没有区域聚类，这表明密切相关的菌株在东南亚传播。
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