Karaev Z O, Sardyko N V, Lebedeva T N, Pokrovskaia O L, Golikova E A
Zh Mikrobiol Epidemiol Immunobiol. 1987 Nov(11):63-8.
To compare the clinical picture and the immunological characteristics, 58 candidiasis patients differing by the severity and dissemination of the disease were examined. Chronic candidiasis of the skin and mucous membranes, the most severe and disseminated form of the disease, is associated with a decrease in the number of T-lymphocytes and changes in their subpopulations, as well as high titers of Candida albicans antigen and antibodies to it in blood sera. The immune system of patients with visceral candidiasis and chronic vulvovaginal candidiasis was similar to that of healthy persons in the characteristics under study. Immediate and mixed hypersensitivity occurred in candidiasis patients more frequently than in healthy persons. In extremely severe forms of Candida infection immediate hypersensitivity prevailed.
为比较临床表现和免疫学特征，对58例病情严重程度和播散情况各异的念珠菌病患者进行了检查。皮肤和黏膜慢性念珠菌病是该病最严重和播散性的形式，与T淋巴细胞数量减少及其亚群变化有关，同时血清中白色念珠菌抗原和抗体滴度较高。内脏念珠菌病和慢性外阴阴道念珠菌病患者的免疫系统在所研究的特征方面与健康人相似。念珠菌病患者出现速发型和混合型超敏反应的频率高于健康人。在极其严重的念珠菌感染形式中，速发型超敏反应占主导。
