Hahn R G
Department of Anaesthesiology, Huddinge University Hospital, Sweden.
Acta Anaesthesiol Scand. 1987 Nov;31(8):680-3. doi: 10.1111/j.1399-6576.1987.tb02645.x.
A mean decrease in the arterial serum potassium concentration (S-K) of 0.40 mmol/l (range 0-1.0) was found in 45 elderly men who were studied before and after induction of epidural anaesthesia (using mepivacaine 2% with adrenaline). The decrease was similar in patients who received acetated Ringer solution or dextran 40 in normal saline as intravenous fluid supplementation. No difference in S-K change was found between patients with a normal (less than 115 mumol/l) or elevated serum creatinine concentration. The decrease in S-K prevailed at the end of surgery except in patients with an elevated serum creatinine. Corrections of S-K for changes in arterial blood pH and rectal temperature during induction of anaesthesia did not explain the decrease in S-K. Correlations of clinical parameters such as the extension of anaesthesia, amount of intravenous fluid given and blood pressure changes gave conflicting results. A smaller decrease or no change in S-K was usually seen in arterial (n = 7) and venous (n = 7) samples when no intravenous fluid was given, as well as in venous samples when acetated Ringer solution was given (n = 6).
对45名老年男性在硬膜外麻醉诱导前后（使用2%甲哌卡因加肾上腺素）进行研究，发现动脉血清钾浓度（S-K）平均降低0.40 mmol/l（范围0 - 1.0）。在接受醋酸林格液或右旋糖酐40生理盐水作为静脉补液的患者中，这种降低情况相似。血清肌酐浓度正常（低于115 μmol/l）或升高的患者之间，S-K变化无差异。除血清肌酐升高的患者外，S-K降低在手术结束时仍然存在。麻醉诱导期间，针对动脉血pH值和直肠温度变化对S-K进行校正，无法解释S-K的降低。麻醉范围、静脉补液量和血压变化等临床参数之间的相关性得出了相互矛盾的结果。当不给予静脉补液时，动脉血样本（n = 7）和静脉血样本（n = 7）中通常可见S-K降低幅度较小或无变化，给予醋酸林格液时静脉血样本（n = 6）中也是如此。
