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住宅和宿舍灰尘中的邻苯二甲酸酯:出现、人体暴露和风险评估。

Phthalates in House and Dormitory Dust: Occurrence, Human Exposure and Risk Assessment.

机构信息

Institute for Advanced Study, Shenzhen University, Shenzhen, 518060, China.

Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China.

出版信息

Bull Environ Contam Toxicol. 2021 Feb;106(2):393-398. doi: 10.1007/s00128-020-03058-7. Epub 2020 Nov 28.

Abstract

Phthalates are one of ubiquitous contaminants in the indoor environment. In this study, we analyzed concentrations and profiles of 9 phthalates in dust samples collected from houses and university dormitories in Nanjing, China. The total concentrations of phthalates in house and dormitory dust ranged from 111.4 to 3599.1 µg/g and 86.1 to 1262.3 µg/g, respectively. Phthalates in house was significantly higher than that in dormitory dust (p < 0.01). Di(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP) and di-isobutyl phthalate (DiBP) were the three predominant compounds and accounted for more than 98% of total phthalates in the two microenvironments. The estimated daily intake (EDI) of phthalates, carcinogenic risk (CR) of DEHP, and hazard index (HI) values of DEHP, DBP and DiBP were estimated. Except for adults, the CR of DEHP for four subgroups (infants, toddlers, children, and teenagers) had exceeded the limitation, implying that they are at the risk of exposure to DEHP through dust ingestion.

摘要

邻苯二甲酸酯是室内环境中普遍存在的污染物之一。本研究分析了中国南京的房屋和大学宿舍灰尘样本中 9 种邻苯二甲酸酯的浓度和分布情况。房屋和宿舍灰尘中邻苯二甲酸酯的总浓度范围分别为 111.4 至 3599.1 µg/g 和 86.1 至 1262.3 µg/g。房屋中的邻苯二甲酸酯明显高于宿舍灰尘(p<0.01)。邻苯二甲酸二(2-乙基己基)酯(DEHP)、邻苯二甲酸二丁酯(DBP)和邻苯二甲酸二异丁酯(DiBP)是三种主要化合物,占两种微环境中总邻苯二甲酸酯的 98%以上。估计了邻苯二甲酸酯的每日摄入量(EDI)、DEHP 的致癌风险(CR)和 DEHP、DBP 和 DiBP 的危害指数(HI)值。除成年人外,四个亚组(婴儿、学步儿童、儿童和青少年)的 DEHP CR 均超过了限制,这表明他们通过灰尘摄入 DEHP 的风险。

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