Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Hepatology Services, Rush University Medical Center, Chicago, IL, United States.
J Hepatol. 2021 Mar;74(3):734-741. doi: 10.1016/j.jhep.2020.11.027. Epub 2020 Nov 25.
Despite the remarkable advances in HCV treatment brought about by the advent of direct-acting antivirals, HCV remains a global public health concern. One particular concern relates to the rising prevalence of HCV in women of childbearing age. Active HCV during pregnancy is associated with cholestasis of pregnancy as well as the risk of mother-to-child transmission. Guidelines are increasingly recommending universal screening during pregnancy, while the treatment of HCV during pregnancy is an area of ongoing research.
尽管直接作用抗病毒药物的出现带来了 HCV 治疗的显著进展，但 HCV 仍然是全球公共卫生关注的问题。一个特别关注的问题涉及到生育年龄妇女中 HCV 的患病率上升。怀孕期间的活动性 HCV 与妊娠胆汁淤积症以及母婴传播的风险有关。指南越来越多地建议在怀孕期间进行普遍筛查，而怀孕期间 HCV 的治疗是一个正在研究的领域。
