Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland.
Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland.
Drug Alcohol Depend. 2021 Jan 1;218:108427. doi: 10.1016/j.drugalcdep.2020.108427. Epub 2020 Nov 23.
Alcohol consumption is one of the risk factors associated with over 200 types of diseases, being strongly correlated with unemployment, low socioeconomic status, traffic accidents, and violence. Alcohol is also one of the main causes of premature deaths, especially among males. Early diagnosis based on screening may help to prevent the evolution from alcohol misuse to dependence by counseling or treatment.
1024 participants took part in the study: 300 of alcohol dependents and 724 of controls (405 students and 319 patients from General Practice) (M ± SD age = 33.7 ± 15.4 years). Finally, group of 877 participants were included to the statistical analysis due to the missing data - 453 were male and 424 were female. The median AUDIT score was 17 (IQR = 11).
Correlation analysis showed that AUDIT scores were strongly correlated with MAST (rho = 0.764, p < 0.001) and CAGE scores (rho = 759, p < 0.001). The ROC analysis resulted in an area under the curve (AUC) of 0.95 (p < 0.001; 95 % C.I.: 0.936-0.963). The cutoff point of 22 for alcohol dependence corresponded to a sensitivity of 0.893 and a specificity of 0.863.
According to our results, the AUDIT scale proved to be a useful tool with high sensitivity and specificity and therefore can be used as a valid screening measure in Poland.
饮酒是与 200 多种疾病相关的风险因素之一，与失业、社会经济地位低下、交通事故和暴力密切相关。酒精也是导致早逝的主要原因之一，尤其是在男性中。基于筛查的早期诊断可以通过咨询或治疗帮助防止酒精滥用发展为依赖。
共有 1024 名参与者参加了这项研究：300 名酒精依赖者和 724 名对照者（405 名学生和 319 名普通科患者）（M ± SD 年龄=33.7 ± 15.4 岁）。最后，由于数据缺失，共有 877 名参与者被纳入统计分析 - 453 名男性和 424 名女性。AUDIT 评分的中位数为 17（IQR=11）。
相关性分析表明，AUDIT 评分与 MAST（rho=0.764，p<0.001）和 CAGE 评分（rho=0.759，p<0.001）高度相关。ROC 分析得出曲线下面积（AUC）为 0.95（p<0.001；95%置信区间：0.936-0.963）。酒精依赖的截断值为 22，其灵敏度为 0.893，特异性为 0.863。
根据我们的结果，AUDIT 量表被证明是一种有用的工具，具有高灵敏度和特异性，因此可以在波兰用作有效的筛查措施。
