用于检测急性恶性疟原虫疟疾抗原的酶免疫测定法。
Enzyme immunoassay for detection of antigen in acute Plasmodium falciparum malaria.
作者信息
Fortier B, Delplace P, Dubremetz J F, Ajana F, Vernes A
机构信息
Unité 42 INSERM, Villeneuve d'Ascq, France.
出版信息
Eur J Clin Microbiol. 1987 Oct;6(5):596-8. doi: 10.1007/BF02014260.
PMID:3325286
Abstract
A monoclonal antibody specific for an epitope of a 50 kDa Plasmodium falciparum antigen was used in an enzyme immunoassay for detection of the corresponding exo-antigen in culture supernatant and in the sera of 31 patients suffering from acute malaria. The assay was specific for Plasmodium falciparum and did not appear to be strain restricted. A parasitaemia level below 0.001% could be detected.
摘要
一种针对恶性疟原虫50 kDa抗原表位的单克隆抗体被用于酶免疫测定，以检测培养上清液及31例急性疟疾患者血清中的相应外抗原。该测定对恶性疟原虫具有特异性，且似乎不受菌株限制。可检测到低于0.001%的寄生虫血症水平。
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