G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of Russian Academy of Sciences, Pr. 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
Mar Drugs. 2020 Nov 24;18(12):584. doi: 10.3390/md18120584.
Asterosaponins are a class of steroid oligoglycosides isolated from starfish with characteristic structures and diverse biological activities. In this review, we have attempted to combine the most important data concerning asterosaponins and give a list of these secondary metabolites with their structural peculiarities. The purpose of this review is to provide a brief but as complete as possible principal information about their chemical structures, taxonomic distribution in the marine environment, distribution in different geographical areas and depths, some properties, biological activities, and functions. Some other rare steroid metabolites from starfish, closely related in structures and probably biogenesis to asterosaponins, are also discussed.
海星甾苷是一类甾体寡糖苷,从海星中分离得到,具有特征结构和多种生物活性。在本综述中,我们试图结合有关海星甾苷的最重要数据,并列出这些具有结构特殊性的次生代谢产物。本综述的目的是提供有关其化学结构、在海洋环境中的分类分布、在不同地理区域和深度的分布、某些性质、生物活性和功能的简要但尽可能完整的主要信息。本文还讨论了一些其他来自海星的罕见甾体代谢物,它们在结构和生物发生上与海星甾苷密切相关。