Riva Ivano, Micheletti Eleonora, Oddone Francesco, Bruttini Carlo, Montescani Silvia, De Angelis Giovanni, Rovati Luigi, Weinreb Robert N, Quaranta Luciano
IRCCS-Fondazione Bietti, 00198 Rome, Italy.
Department of Surgical and Clinical, Diagnostic and Pediatric Sciences, Section of Ophthalmology, University of Pavia, IRCCS Fondazione Policlinico San Matteo, 27100 Pavia, Italy.
J Clin Med. 2020 Nov 25;9(12):3814. doi: 10.3390/jcm9123814.
Assessment of the anterior chamber angle (ACA) is an essential part of the ophthalmological examination. It is intrinsically related to the diagnosis and treatment of glaucoma and has a role in its prevention. Although slit-lamp gonioscopy is considered the gold-standard technique for ACA evaluation, its poor reproducibility and the long learning curve are well-known shortcomings. Several new imaging techniques for angle evaluation have been developed in the recent years. However, whether these instruments may replace or not gonioscopy in everyday clinical practice remains unclear. This review summarizes the last findings in ACA evaluation, focusing on new instruments and their application to the clinical practice. Special attention will be given to the comparison between these new techniques and traditional slit-lamp gonioscopy. Whereas ultrasound biomicroscopy and anterior segment optical coherence tomography provide quantitative measurements of the anterior segment's structures, new gonio-photographic systems allow for a qualitative assessment of angle findings, similarly to gonioscopy. Recently developed deep learning algorithms provide an automated classification of angle images, aiding physicians in taking faster and more efficient decisions. Despite new imaging techniques made analysis of the ACA more objective and practical, the ideal method for ACA evaluation has still to be determined.
前房角(ACA)评估是眼科检查的重要组成部分。它与青光眼的诊断和治疗密切相关,并在青光眼的预防中发挥作用。尽管裂隙灯前房角镜检查被认为是评估前房角的金标准技术,但其可重复性差和学习曲线长是众所周知的缺点。近年来,已经开发了几种用于前房角评估的新成像技术。然而,这些仪器在日常临床实践中是否可以取代前房角镜检查尚不清楚。本综述总结了前房角评估的最新研究结果,重点关注新仪器及其在临床实践中的应用。将特别关注这些新技术与传统裂隙灯前房角镜检查之间的比较。超声生物显微镜和眼前节光学相干断层扫描可提供眼前节结构的定量测量,而新的前房角摄影系统则可以像前房角镜检查一样对前房角检查结果进行定性评估。最近开发的深度学习算法可对前房角图像进行自动分类,帮助医生做出更快、更有效的决策。尽管新的成像技术使前房角分析更加客观和实用,但前房角评估的理想方法仍有待确定。