Spine Department 2, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China.
State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, Jiangsu Province, China.
J Tradit Chin Med. 2020 Dec;40(6):1033-1040. doi: 10.19852/j.cnki.jtcm.2020.06.015.
To investigate the effect of spinal manipulation (SM) on degenerative scoliosis by evaluating patients' visual analog scale (VAS) scores, Cobb angles, sagittal vertical axis (SVA), and apical vertebral rotation (AVR) and to explore factors that influence treatment effect.
A total of 55 patients with degenerative scoliosis received 4 weeks of SM. After treatment, patients were divided into two groups: the remission group (VAS score < 40 mm) and the non-remission group (VAS score ≥ 40 mm). Pre- versus post-treatment VAS scores, Cobb angles, SVA, and AVR were compared in each group and in the total population. Baseline data (sex, age, symptom characteristics, duration of symptoms, VAS score, Cobb angle, SVA, and AVR) were compared between groups. Factors influencing the post-treatment VAS score were explored with multiple linear regression analysis.
No changes were found in the Cobb angle (P = 0.722) or AVR (P = 0.424) after intervention in the overall population. However, the SVA (P < 0.001) and VAS score (P = 0.000) changed significantly after treatment. Similar changes were observed in the remission group (n = 29). Multiple linear regression revealed that the only factors influencing treatment effect were symptom characteristics, SVA, and VAS score.
SM relieved pain and improved sagittal imbalance in patients with degenerative scoliosis. It did not lessen the severity of coronal curvature or vertebral rotation. Factors influencing the effect of SM included symptom characteristics, VAS score, and SVA. A larger randomized trial is needed to further confirm our results.
通过评估患者的视觉模拟评分(VAS)、Cobb 角、矢状垂直轴(SVA)和顶椎旋转(AVR),研究脊柱手法(SM)对退行性脊柱侧凸的影响,并探讨影响治疗效果的因素。
共 55 例退行性脊柱侧凸患者接受了 4 周的 SM 治疗。治疗后,患者分为缓解组(VAS 评分<40mm)和未缓解组(VAS 评分≥40mm)。比较各组和总体人群治疗前后的 VAS 评分、Cobb 角、SVA 和 AVR。比较组间基线数据(性别、年龄、症状特征、症状持续时间、VAS 评分、Cobb 角、SVA 和 AVR)。采用多元线性回归分析探讨影响治疗后 VAS 评分的因素。
总体人群干预后 Cobb 角(P=0.722)或 AVR(P=0.424)无变化。然而,SVA(P<0.001)和 VAS 评分(P=0.000)在治疗后明显改变。缓解组(n=29)也观察到类似的变化。多元线性回归显示,影响治疗效果的唯一因素是症状特征、SVA 和 VAS 评分。
SM 缓解了退行性脊柱侧凸患者的疼痛并改善了矢状面失衡,但对冠状面曲率或椎体旋转的严重程度没有减轻。影响 SM 效果的因素包括症状特征、VAS 评分和 SVA。需要更大规模的随机试验来进一步证实我们的结果。