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兔自发性鼻腔肿瘤:7 例报告(2007-2019 年)。

Spontaneous intranasal tumours in rabbits: 7 cases (2007-2019).

机构信息

Miwa Exotic Animal Hospital, 1-25-5, Komagome, Toshima-ku, Tokyo, Japan, 170003.

Veterinary Medical Center, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, Japan, 1138657.

出版信息

J Small Anim Pract. 2021 May;62(5):379-384. doi: 10.1111/jsap.13268. Epub 2020 Dec 1.

Abstract

OBJECTIVES

Neoplasms that arise in the nasal cavity are reported infrequently in rabbits. This case series aims to review and determine the clinical behaviour of neoplasms in the nasal cavity in rabbits.

MATERIALS AND METHODS

A retrospective study was conducted on seven pet rabbits diagnosed with intranasal tumours to describe the clinical and histopathological findings and prognoses after surgery and/or radiotherapy.

RESULTS

The most common clinical signs were nasal snoring when breathing, nasal discharge, and subsequent dyspnoea and anorexia. Six different histopathological types of tumours were diagnosed: intranasal adenocarcinoma, squamous cell carcinoma, osteosarcoma, carcinoid tumour, osteoma, and lymphoma. Skull radiography only revealed the abnormalities in three of seven cases but on CT, the intranasal masses were more clearly identified in all cases. All cases received tumour resection through rhinostomy and four cases received radiotherapy after surgery. In the six cases with a known outcome, the survival time after surgery was more than 13 months.

CLINICAL SIGNIFICANCE

This case series provides an insight of the behavior of intranasal neoplasms in rabbits. Surgical treatment and radiotherapy could improve their clinical sings.

摘要

目的

鼻腔内发生的肿瘤在兔子中报道较少。本病例系列旨在回顾和确定兔子鼻腔内肿瘤的临床行为。

材料和方法

对 7 只被诊断为鼻腔内肿瘤的宠物兔进行回顾性研究,以描述手术和/或放疗后的临床和组织病理学发现和预后。

结果

最常见的临床症状是呼吸时的鼻腔呼噜声、鼻腔分泌物,随后出现呼吸困难和食欲不振。诊断出 6 种不同的组织病理学类型的肿瘤:鼻腔腺癌、鳞状细胞癌、骨肉瘤、类癌肿瘤、骨瘤和淋巴瘤。颅骨 X 光片仅在 7 例中的 3 例中显示异常,但在 CT 上,所有病例的鼻腔内肿块都更清晰地显示出来。所有病例均通过鼻造口术进行肿瘤切除,4 例术后接受放疗。在已知结果的 6 例中,手术后的生存时间超过 13 个月。

临床意义

本病例系列提供了对兔子鼻腔内肿瘤行为的深入了解。手术治疗和放疗可以改善它们的临床症状。

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