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心理社会支持干预对改善青少年艾滋病毒感染者接受抗逆转录病毒治疗的依从性和保留率的作用:系统评价。

Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): a scoping review.

机构信息

School of Public Health, University of the Western Cape, P Bag X17 , Bellville, Cape Town, 7535, South Africa.

出版信息

BMC Public Health. 2020 Dec 1;20(1):1841. doi: 10.1186/s12889-020-09717-y.


DOI:10.1186/s12889-020-09717-y
PMID:33261566
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7708133/
Abstract

BACKGROUND: Mental health disorders such as high levels of anxiety, isolation, depression and suicide ideation reported among young people living with HIV (10-24 years;YPLHIV) contribute significantly to poor medication adherence and retention in care. While there is evidence supporting the role of psychosocial support interventions in promoting adherence and retention in antiretroviral treatment (ART) among adults living with HIV, there is little evidence on the role of psychosocial support on medication adherence among YPLHIV. This scoping review was designed to identify and classify the types and effects of psychosocial support interventions designed to improve adherence and retention in ART among YPLHIV globally. METHOD: We searched six electronic databases (i.e., Scopus, Pubmed and EBSCOHost (Academic Search Premier, CINAHL, Psycarticles and Medline). Six relevant articles published between 2011 and 2019 met our inclusion criteria. We extracted information relevant to the nature and outcomes of the reported interventions using thematic content analysis informed by the Population, Intervention, comparison, outcome, and time (PICOT) framework. RESULTS: Four distinctive treatment modalities that focused on improving ART adherence and retention in care were identified: individual counselling, support groups, family-centered services, and treatment supporters. CONCLUSION: There is a dearth of psychosocial support interventions to improve adherence and retention in ART amongst adolescents and young adults living with HIV. Future research and programming should seek to address psychosocial support interventions or approaches specifically designed to address the needs of YPLHIV. TRIAL REGISTRATION: PROSPERO: Registration CRD42018105057 .

摘要

背景:在感染艾滋病毒的年轻人(10-24 岁;YPLHIV)中,焦虑、孤立、抑郁和自杀意念等心理健康障碍的报告比例很高,这对药物依从性和保持治疗状态产生了重大影响。虽然有证据支持心理社会支持干预在促进成年 HIV 感染者的药物依从性和保持治疗方面的作用,但在 YPLHIV 中,心理社会支持对药物依从性的作用的证据很少。本范围综述旨在确定和分类旨在提高 YPLHIV 全球抗逆转录病毒治疗(ART)药物依从性和保留率的心理社会支持干预措施的类型和效果。

方法:我们搜索了六个电子数据库(即 Scopus、PubMed 和 EBSCOHost(学术搜索高级版、CINAHL、Psycarticles 和 Medline)。符合我们纳入标准的六篇相关文章发表于 2011 年至 2019 年之间。我们使用主题内容分析提取了与报告干预措施的性质和结果相关的信息,该分析受到人口、干预、比较、结果和时间(PICOT)框架的启发。

结果:确定了四种独特的治疗方式,重点是提高 ART 依从性和保持治疗状态:个体咨询、支持小组、以家庭为中心的服务和治疗支持者。

结论:针对艾滋病毒感染的青少年和年轻成年人,改善 ART 依从性和保持治疗状态的心理社会支持干预措施很少。未来的研究和规划应寻求解决心理社会支持干预措施或专门针对 YPLHIV 需求设计的方法。

试验注册:PROSPERO:注册 CRD42018105057 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ab/7708133/cb980790561c/12889_2020_9717_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ab/7708133/cb980790561c/12889_2020_9717_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ab/7708133/cb980790561c/12889_2020_9717_Fig1_HTML.jpg

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本文引用的文献

[1]
Effect of a differentiated service delivery model on virological failure in adolescents with HIV in Zimbabwe (Zvandiri): a cluster-randomised controlled trial.

Lancet Glob Health. 2020-1-7

[2]
Household-focused interventions to enhance the treatment and management of HIV in low- and middle-income countries: a scoping review.

BMC Public Health. 2019-12-16

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