Santaella Natalia-Garcia, Maciel Aloizio-Premoli, Simpione Guilherme, Santos Paulo-Sérgio-da Silva
Department of surgery, stomatology, pathology and radiology, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
J Clin Exp Dent. 2020 Nov 1;12(11):e1045-e1049. doi: 10.4317/jced.57282. eCollection 2020 Nov.
Halitosis is a condition that affects 50% of adults and one third of patients with chronic kidney disease. The aim of this study was to evaluate oral manifestations and volatile sulfur compounds (VSCs) associated with halitosis and quality of life in pre-kidney transplantation candidates.
The organoleptic test (OT) and halimetry (HA) (before and after cysteine mouthwash) were performed in patients with the Oralchroma® device, stimulated (SE) and non-stimulated sialometry (SN), Tongue Coating Index (TCI). The OHIP-14 questionnaire was administered to assess the impact of oral health on quality of life.
Fourteen individuals with a mean age of 49.64 ± 13.35 years were evaluated. In the organoleptic test, 57.14% of the individuals presented halitosis. Oralchroma results showed that dimethyl sulfide was above the threshold in 85.71% of the individuals, while hydrogen sulfide and methyl mercaptan were above threshold in 28.57%; after the use of cysteine, hydrogen sulfide was present in 100% of the cases, dimethyl sulfide in 57.14% and methyl mercaptan in 50%. In the non-stimulated sialometry, 57.14% of the individuals presented hyposalivation and 21.42% in the stimulated. Regarding the tongue coating index, 100% of the individuals presented tongue coating, with a mean of 7.64. The assessment of impact of oral health on quality of life showed a negative impact in all dimensions.
Tongue coating, in association with hydrogen sulfide, was the main cause of halitosis in the study subjects, and hyposalivation may contribute to higher tongue-coating indices. These oral changes negatively affect the quality of life for pre-kidney transplantation patients. Halitosis, chronic kidney disease, quality of life, kidney transplantation.
口臭是一种影响50%的成年人及三分之一慢性肾病患者的病症。本研究的目的是评估肾移植术前候选者中与口臭相关的口腔表现、挥发性硫化物（VSC）及生活质量。
使用Oralchroma®设备对患者进行感官测试（OT）和比色法（HA）（使用半胱氨酸漱口水前后）、刺激唾液分泌量测定（SE）和非刺激唾液分泌量测定（SN）、舌苔指数（TCI）。采用OHIP-14问卷评估口腔健康对生活质量的影响。
评估了14名平均年龄为49.64±13.35岁的个体。在感官测试中，57.14%的个体存在口臭。Oralchroma结果显示，85.71%的个体二甲基硫高于阈值，而硫化氢和甲硫醇高于阈值的个体为28.57%；使用半胱氨酸后，100%的病例出现硫化氢，57.14%出现二甲基硫，50%出现甲硫醇。在非刺激唾液分泌量测定中，57.14%的个体唾液分泌减少，刺激唾液分泌量测定中为21.42%。关于舌苔指数，100%的个体有舌苔，平均为7.64。口腔健康对生活质量影响的评估显示在所有维度均有负面影响。
舌苔与硫化氢相关，是研究对象口臭的主要原因，唾液分泌减少可能导致舌苔指数更高。这些口腔变化对肾移植术前患者的生活质量产生负面影响。口臭、慢性肾病、生活质量、肾移植。
