Department of Electrical and Electronic Information Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.
Japan Society for the Promotion of Science, Tokyo 102-0083, Japan.
Sensors (Basel). 2020 Nov 30;20(23):6868. doi: 10.3390/s20236868.
Disease screening by exhaled breath diagnosis is less burdensome for patients, and various devices have been developed as promising diagnostic methods. We developed a microelectromechanical system (MEMS) optical interferometric surface stress sensor to detect volatile ethanol gas at room temperature (26~27 °C) with high sensitivity. A sub-micron air gap in the optical interferometric sensor reduces interference orders, leading to increased spectral response associated with nanomechanical deflection caused by ethanol adsorption. The sub-micron cavity was embedded in a substrate using a transfer technique of parylene-C nanosheet. The sensor with a 0.4 µm gap shows a linear stable reaction, with small standard deviations, even at low ethanol gas concentrations of 5-110 ppm and a reversible reaction to the gas concentration change. Furthermore, the possibility of detecting sub-ppm ethanol concentration by optimizing the diameter and thickness of the deformable membrane is suggested. Compared with conventional MEMS surface stress gas sensors, the proposed optical interferometric sensor demonstrated high-sensitivity gas detection with exceeding the detection limit by two orders of magnitude while reducing the sensing area.
呼气诊断疾病的筛查对患者的负担较小,已经开发出各种设备作为有前途的诊断方法。我们开发了一种微机电系统(MEMS)光学干涉表面应力传感器,以在室温(26~27°C)下高灵敏度检测挥发性乙醇气体。光学干涉传感器中的亚微米气隙减少了干涉级,导致与乙醇吸附引起的纳米机械挠度相关的光谱响应增加。亚微米腔通过聚对二甲苯-C 纳米片的转移技术嵌入在基底中。具有 0.4 µm 间隙的传感器显示出线性稳定的反应,具有较小的标准偏差,即使在低乙醇气体浓度为 5-110 ppm 时也是如此,并且对气体浓度变化具有可逆反应。此外,通过优化可变形膜的直径和厚度,提出了检测亚 ppm 乙醇浓度的可能性。与传统的 MEMS 表面应力气体传感器相比,所提出的光学干涉传感器在降低检测面积的同时,通过提高两个数量级的检测极限,实现了高灵敏度的气体检测。