氧化镁治疗胃食管反流病的疗效：一项随机交叉双盲研究的事后分析。
Effectiveness of almagate in gastroesophageal reflux disease: a post-hoc analysis of a randomized cross-over double-blind study.
机构信息
Digestive Diseases, Centro Médico Teknon, España.
Medical Affairs, Almirall, España.
出版信息
Rev Esp Enferm Dig. 2021 Jun;113(6):479. doi: 10.17235/reed.2020.7449/2020.
Almagate (aluminium-magnesium hydroxycarbonate hydrate) is a widely used antacid in Spain as an over-the-counter formulation. However, data on the control of acidity in patients with gastroesophageal reflux disease (GERD) are scarce. Herein we report a post-hoc analysis of a randomized crossover double-blind trial (ALR-006; data on file), in which equivalent single oral doses (1.5 g) of two formulations of almagate (AlmaxRetard® and Almax®, Laboratorios Almirall, Barcelona, Spain) were both effective for reflux esophagitis.
水合铝镁羟碳酸铝是一种在西班牙广泛使用的抗酸剂，作为一种非处方制剂。然而，关于其用于治疗胃食管反流病（GERD）患者的酸控制效果的数据却很少。在此，我们报告了一项随机交叉双盲试验（ALR-006；档案数据）的事后分析，该试验中两种水合铝镁羟碳酸铝制剂（AlmaxRetard®和 Almax®，均来自西班牙巴塞罗那的 Laboratorios Almirall）的单一口服等效剂量（1.5 g）均对反流性食管炎有效。
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