Department of Pulmonary Medicine, Akershus University Hospital, Lørenskog, Norway
Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.
Thorax. 2021 Apr;76(4):405-407. doi: 10.1136/thoraxjnl-2020-216377. Epub 2020 Dec 3.
This study assessed symptoms and their determinants 1.5-6 months after symptom onset in non-hospitalised subjects with confirmed COVID-19 until 1 June 2020, in a geographically defined area. We invited 938 subjects; 451 (48%) responded. They reported less symptoms after 1.5-6 months than during COVID-19; median (IQR) 0 (0-2) versus 8 (6-11), respectively (p<0.001); 53% of women and 67% of men were symptom free, while 16% reported dyspnoea, 12% loss/disturbance of smell, and 10% loss/disturbance of taste. In multivariable analysis, having persistent symptoms was associated with the number of comorbidities and number of symptoms during the acute COVID-19 phase.
本研究评估了症状及其决定因素在地理定义区域内，2020 年 6 月 1 日之前，在确诊 COVID-19 但未住院的患者症状出现后 1.5-6 个月的情况。我们邀请了 938 名受试者；451 名（48%）做出了回应。与 COVID-19 期间相比，他们在 1.5-6 个月后报告的症状更少；中位数（IQR）分别为 0（0-2）和 8（6-11）（p<0.001）；53%的女性和 67%的男性无症状，而 16%报告呼吸困难，12%报告嗅觉丧失或障碍，10%报告味觉丧失或障碍。在多变量分析中，持续存在的症状与合并症的数量和急性 COVID-19 期间症状的数量有关。
