Department of Otolaryngology, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Department of Otorhinolaryngology, University Hospital of Basel, Basel, Switzerland.
Acta Otolaryngol. 2021 Mar;141(3):299-302. doi: 10.1080/00016489.2020.1855366. Epub 2020 Dec 12.
It has been noted that olfactory and gustatory disturbances may precede or accompany the typical features of COVID-19, such as fever and cough. Hence, a high index of suspicion is required when patients report sudden loss of smell or taste, in order to facilitate timely diagnosis and isolation. The aim of this study was to assess the frequency of olfactory and gustatory disturbances in COVID-19 positive patients from a cohort representative of Melbourne, Australia. A retrospective descriptive study was conducted on patients who tested positive for COVID-19. Standardised phone consultations and online follow-up questionnaires were performed to assess clinical features of COVID-19, with a focus on smell and taste disorders. The most frequent symptoms experienced were taste and smell disturbances with 74% experiencing either smell or taste disturbance or both. Post-recovery, 34% of patients continued to experience ongoing hyposmia and 2% anosmia, whereas 28% continued to suffer from hypogeusia or ageusia. This study presents the high rates of improvement of both olfactory and gustatory disturbance in a short-lived period. It also highlights the importance of these symptoms in prompting appropriate testing, quarantine precautions, initiate early olfactory retraining and the potential for continued sensory disturbance.
已经注意到,嗅觉和味觉障碍可能先于或伴随 COVID-19 的典型特征出现,例如发热和咳嗽。因此,当患者报告突然失去嗅觉或味觉时,需要高度怀疑,以便及时进行诊断和隔离。本研究旨在评估来自澳大利亚墨尔本代表性队列的 COVID-19 阳性患者中嗅觉和味觉障碍的频率。对 COVID-19 检测呈阳性的患者进行了回顾性描述性研究。进行了标准化的电话咨询和在线随访问卷,以评估 COVID-19 的临床特征,重点是嗅觉和味觉障碍。最常经历的症状是味觉和嗅觉障碍,74%的患者出现嗅觉或味觉障碍或两者兼有。康复后,34%的患者持续出现嗅觉减退,2%的患者出现嗅觉丧失,而 28%的患者持续出现味觉减退或味觉丧失。本研究表明,在短时间内,嗅觉和味觉障碍的改善率很高。它还强调了这些症状在提示进行适当检测、隔离预防措施、早期嗅觉训练以及持续感觉障碍方面的重要性。