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新冠康复后在年轻人中的情况——患病率及其与总体健康、压力和生活方式因素的关联

Post COVID-19 among young adults- prevalence and associations with general health, stress, and lifestyle factors.

作者信息

Ekström Sandra, Mogensen Ida, Ödling Maria, Georgelis Antonios, Merritt Anne-Sophie, Björkander Sophia, Melén Erik, Bergström Anna, Kull Inger

机构信息

Center for Occupational and Environmental Medicine, Region Stockholm, Stockholm, 113 65, Sweden.

Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, 118 83, Sweden.

出版信息

BMC Public Health. 2025 Apr 9;25(1):1330. doi: 10.1186/s12889-025-22522-9.

Abstract

BACKGROUND

The prevalence of post COVID-19 condition (PCC) after mild infection among young adults is largely unknown, as are its impact on health and lifestyle factors.

OBJECTIVE

To assess the prevalence of PCC among young adults and its impact on general health, stress, and changes in lifestyle factors three years after the onset of the pandemic.

METHODS

The study population (n = 2,098) included participants from the population-based cohort BAMSE (aged 27-30 years). PCC symptoms and changes in lifestyle factors during the pandemic were assessed in a questionnaire distributed in September-December 2023 and analyzed cross-sectionally. Stress, physical activity, and general health were also assessed pre-pandemic (2016-2019) and analyzed longitudinally. PCC was defined as ≥ 1 symptom lasting for ≥ 2 months after COVID-19.

RESULTS

In total, 1,577 (75.5%) reported previous COVID-19. Among these, 166 (10.5%) reported previous and 62 (3.9%) ongoing PCC. The most common ongoing symptoms were altered smell/taste, psychological symptoms, and fatigue. Both pre- and post-pandemic general health differed significantly in relation to PCC in cross-sectional analyzes (all p < 0.05), with the lowest health reported by those with ongoing PCC. Participants with ongoing PCC also had a reduction in well-being in longitudinal analyses (p = 0.04). This group also reported more adverse changes in lifestyle factors and health during the pandemic such as reduced physical activity (p < 0.001) and worsened dietary habits (p = 0.03). However, there was no significant difference in the longitudinally measured perceived stress scale among individuals with PCC.

CONCLUSIONS

Almost 4% of young adults with previous self-reported COVID-19 had ongoing symptoms of PCC three years after the onset of the pandemic. This group reported poorer health and more adverse changes in lifestyle factors than participants without PCC. Targeted healthcare interventions for young adults with PCC are warranted.

摘要

背景

年轻人轻度感染新冠病毒后新冠后状况(PCC)的患病率很大程度上未知,其对健康和生活方式因素的影响也不清楚。

目的

评估大流行开始三年后年轻人中PCC的患病率及其对总体健康、压力和生活方式因素变化的影响。

方法

研究人群(n = 2098)包括来自基于人群的队列BAMSE(年龄27 - 30岁)的参与者。在2023年9月至12月分发的问卷中评估了大流行期间的PCC症状和生活方式因素变化,并进行横断面分析。还在大流行前(2016 - 2019年)评估了压力、身体活动和总体健康,并进行纵向分析。PCC被定义为新冠病毒感染后持续≥2个月的≥1种症状。

结果

总共1577人(75.5%)报告曾感染新冠病毒。其中,166人(10.5%)报告曾有PCC,62人(3.9%)报告目前患有PCC。最常见的持续症状是嗅觉/味觉改变、心理症状和疲劳。在横断面分析中,大流行前和大流行后的总体健康状况与PCC均有显著差异(所有p < 0.05),目前患有PCC的人报告的健康状况最差。在纵向分析中,目前患有PCC的参与者的幸福感也有所下降(p = 0.04)。该组还报告在大流行期间生活方式因素和健康方面有更多不良变化,如身体活动减少(p < 0.001)和饮食习惯恶化(p = 0.03)。然而,PCC患者在纵向测量的感知压力量表上没有显著差异。

结论

在大流行开始三年后,近4%曾自我报告感染新冠病毒的年轻人有持续的PCC症状。与没有PCC的参与者相比,该组报告的健康状况较差,生活方式因素有更多不良变化。有必要针对患有PCC的年轻人进行有针对性的医疗干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c79a/11984280/339b6994d768/12889_2025_22522_Fig1_HTML.jpg

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