Manabe T, Tanaka Y, Yamaki K, Asano N, Nonaka A, Hirano T, Nishikawa H, Tobe T
First Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
Gastroenterol Jpn. 1987 Dec;22(6):756-8. doi: 10.1007/BF02776750.
Plasma secretin levels were measured during a 72-hour starvation period in dogs. Plasma secretin rose significantly and insulin levels fell significantly during starvation. Intravenous glucose loading at the end of the 72-hour starvation period suppressed plasma secretin and free fatty acid levels with a concomitant rise of glucose and insulin levels. These findings suggest that secretin might be regulated by plasma glucose and insulin levels and might play a role in lipolysis during starvation.
在犬类72小时饥饿期内测量血浆促胰液素水平。饥饿期间血浆促胰液素显著升高，胰岛素水平显著下降。在72小时饥饿期结束时静脉注射葡萄糖，可抑制血浆促胰液素和游离脂肪酸水平，同时血糖和胰岛素水平升高。这些发现表明，促胰液素可能受血浆葡萄糖和胰岛素水平的调节，并可能在饥饿期间的脂肪分解中发挥作用。
