Department of Dermatology, Venereology and Leprosy, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, India.
Dermatol Ther. 2021 Jan;34(1):e14631. doi: 10.1111/dth.14631. Epub 2020 Dec 13.
Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoriasis (GP), and pityriasis lichenoides chronica (PLC) seen over a period of 3 years were included. Dermoscopy images were extracted from photography archives for evaluation and three lesions from each patient (60 lesions each) were analyzed. Comparison of dermoscopy characters was done among PR, GP, and PLC in pairs using chi-square test and a P-value of less than .05 was considered significant. Most common background color in PR (86.7%) and PLC (96.7%) was yellow to yellow-orange and in GP was dull red to pink (70%). Vessels were visualized in all lesions of GP and most characteristic pattern was regular (93.3%), dotted vessels (95%). In PR 63.3% lesions had dotted vessels mostly in a patchy distribution (56.7%). Most prominent scale color in PR was yellow-white (88.3%) and in GP was white-gray (80%). In PLC varying colors were seen, most prominent being brown (53.3%). Characteristic findings seen only in PLC were hypopigmented areas (13.3%), brown dots and globules (53.3%) and orange-yellow structureless areas (61.7%) GP, PR, and PLC reveal specific dermoscopic findings that can help in differentiating them. Further, the known dermoscopic criteria for GP, PR, and PLC also apply for dark skin phototypes.
皮肤镜检查作为一种诊断工具,在炎症性皮肤病中的应用越来越广泛,其对大多数皮肤病特征性表现的累积描述,有时可以替代活检。在这项回顾性观察研究中,纳入了 3 年内确诊的各 20 例玫瑰糠疹(PR)、点滴状银屑病(GP)和慢性苔藓样糠疹(PLC)患者的组织病理学检查结果。从摄影档案中提取皮肤镜图像进行评估,并对每位患者的 3 处病变(共 60 处病变)进行分析。使用卡方检验对 PR、GP 和 PLC 之间的皮肤镜特征进行两两比较,P 值小于 0.05 认为有统计学意义。PR(86.7%)和 PLC(96.7%)最常见的背景颜色为黄色到橙黄色,而 GP 为暗红色到粉红色(70%)。GP 的所有病变中均可观察到血管,最典型的模式为规则(93.3%)、点状血管(95%)。PR 中 63.3%的病变有点状血管,大多呈斑片状分布(56.7%)。PR 中最突出的鳞屑颜色为黄白色(88.3%),GP 为白色-灰色(80%)。PLC 中可见各种颜色,最突出的是棕色(53.3%)。仅在 PLC 中可见特征性表现为色素减退区(13.3%)、棕色斑点和小球(53.3%)以及橙黄色无结构区(61.7%)。GP、PR 和 PLC 均有其独特的皮肤镜表现,有助于鉴别。此外,已知的 GP、PR 和 PLC 的皮肤镜标准也适用于深色皮肤类型。