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采用 Xpert MTB/RIF® 方法诊断皮肤结核(淋巴结瘰疬)。

Diagnosis of cutaneous tuberculosis (lymph node scrofuloderma) using the Xpert MTB/RIF® method.

机构信息

Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.

Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.

出版信息

An Bras Dermatol. 2021 Jan-Feb;96(1):82-84. doi: 10.1016/j.abd.2020.01.009. Epub 2020 Nov 19.

Abstract

Cutaneous tuberculosis is a rare infection that is difficult to diagnose, because it shows less sensitivity and specificity in classic complementary exams when compared with the pulmonary form. The Xpert MTB/RIF® method offers an early diagnosis that identifies the DNA of Mycobacterium tuberculosis and the main mutations that give the bacterium resistance to rifampicin. The authors present a case of scrofuloderma whose diagnosis was quickly obtained through the secretion of a cervical lesion, allowing an early diagnosis and the initiation of appropriate treatment.

摘要

皮肤结核是一种罕见的感染,难以诊断,因为与肺结核形式相比,其在经典的补充检查中显示出较低的敏感性和特异性。Xpert MTB/RIF® 方法提供了一种早期诊断,可以识别结核分枝杆菌的 DNA 以及导致细菌对利福平产生耐药性的主要突变。作者介绍了一例颈部病变分泌物迅速确诊的瘰疬病例,这有助于早期诊断和开始适当的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ff9/7838117/0ea06c2dd702/gr1.jpg

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