Department of Oral and Maxillofacial Surgery, SRM Dental College and Hospital, Ramapuram Campus, Ramapuram, Chennai, 600089, Tamil Nadu, India.
Department of Oral and Maxillofacial Surgery, SRM Dental College and Hospital, Ramapuram Campus, Ramapuram, Chennai, 600089, Tamil Nadu, India.
J Craniomaxillofac Surg. 2021 Jan;49(1):24-28. doi: 10.1016/j.jcms.2020.11.004. Epub 2020 Nov 17.
The aim of this study was to compare the efficacy of dextrose prolotherapy with that of occlusal splints in treating internal derangement of the temporomandibular joint.
A total of 34 patients with temporomandibular joint internal derangement classed as Wilkes stages II or III were recruited for the study, and were randomly divided into study and control groups with 17 patients each. The patients in these control and study groups were treated with splints and prolotherapy, respectively. Outcome parameters, such as pain, mouth opening, clicking and deviation, were assessed using the Helkimo clinical dysfunction index for a review period of 1 year.
Nine patients in the study group had complete absence of pain, compared with only one patient in the control group. The results showed that patients who received prolotherapy demonstrated improvement in pain (p < 0.001), mouth opening (p = 0.032), and clicking (p < 0.001), but no significant difference in deviation was observed between the groups after 1 year (p = 0.862).
Prolotherapy was found to be superior in providing long-term clinical relief, with reduction in pain and clicking along with improved mouth opening.
本研究旨在比较葡萄糖注射疗法与咬合夹板治疗颞下颌关节紊乱症的疗效。
共招募 34 名颞下颌关节紊乱症患者（Wilkes 分期 II 或 III 期），将其随机分为研究组和对照组，每组 17 例。对照组和研究组患者分别接受夹板和注射疗法治疗。采用 Helkimo 临床功能障碍指数评估 1 年的随访期内疼痛、张口度、弹响和偏斜等疗效参数。
研究组 9 例患者完全无疼痛，而对照组仅 1 例。结果显示，接受注射疗法的患者疼痛（p<0.001）、张口度（p=0.032）和弹响（p<0.001）均有改善，但 1 年后两组间偏斜无显著差异（p=0.862）。
注射疗法在提供长期临床缓解方面表现更佳，可减轻疼痛和弹响，同时改善张口度。
