Vaidyanathan Aiswarya, Haidry Naqoosh, Sinha Upasna, Singh Abhishek, Salahudheen Ameera
Department of Dentistry, All India Institute of Medical Sciences, Patna, Bihar, India.
Department of Radiodiagnosis, All India Institute of Medical Sciences, Patna, Bihar, India.
Ann Maxillofac Surg. 2022 Jul-Dec;12(2):166-172. doi: 10.4103/ams.ams_138_22. Epub 2023 Jan 10.
Sclerosing agents have been used for temporomandibular joint (TMJ) hypermobility since decades, some of which are ethanolamine oleate, and OK-432, sodium psylliate (sylnasol), but there are no studies on the usage of polidocanol - a well-known sclerosing agent which does not have much side effects and is inexpensive. Hence, this study evaluates the effect of polidocanol injection in the treatment of TMJ hypermobility.
This was a prospective observational study in which patients with chronic TMJ hypermobility were included. Out of the 44 patients who had symptoms of clicking and pain of the TMJ, 28 were diagnosed as internal derangement of the TMJ. The final analysis included 15 patients in whom multiple injections of polidocanol were given on the basis of post-operative parameters. The sample size was calculated based on a significance level of 0.05 and a power of 80%.
Overall, a success rate of 86.6% (13/15) was encountered at the end of three months, with seven patients not reporting any further episodes of dislocation after one injection and six patients not reporting any episode of dislocation after two injections.
Polidocanol sclerotherapy can be used as a treatment modality for chronic recurrent dislocation of the TMJ, rather than opting for more invasive procedures for the same.
数十年来，硬化剂一直用于治疗颞下颌关节（TMJ）活动过度，其中包括油酸乙醇胺、溶链菌制剂（OK-432）、车前草酸钠（sylnasol），但对于聚多卡醇（一种副作用小且价格低廉的著名硬化剂）的使用尚无相关研究。因此，本研究评估了聚多卡醇注射治疗TMJ活动过度的效果。
这是一项前瞻性观察研究，纳入了慢性TMJ活动过度的患者。在44例有TMJ弹响和疼痛症状的患者中，28例被诊断为TMJ内紊乱。最终分析纳入了15例患者，根据术后参数对其进行了多次聚多卡醇注射。样本量是根据0.05的显著性水平和80%的检验效能计算得出的。
总体而言，三个月结束时的成功率为86.6%（13/15），7例患者注射一次后未再出现脱位情况，6例患者注射两次后未出现脱位情况。
聚多卡醇硬化疗法可作为TMJ慢性复发性脱位的一种治疗方式，而不是选择更具侵入性的手术来治疗同样的疾病。
