Watanabe N, Mikuni K, Nakamura Y
Department of Pediatrics, Kyorin University, Tokyo, Japan.
Jpn Circ J. 1987 Dec;51(12):1350-2. doi: 10.1253/jcj.51.1350.
As the serological test of streptococcal infection, the measurement of anti-exotoxin antibodies such as ASO is widely practiced. M protein of the cell wall of group A streptococcus has type specificity. To detect the anti M protein antibody is very significant, but it is not easy to apply this to clinical practice because there are many types and because of the difficulty of purifying M protein. C polypeptide has group specificity, so the measurement of the antibody to C polypeptide is very important as the serological test of group A streptococcus.
作为链球菌感染的血清学检测，抗外毒素抗体（如抗链球菌溶血素O）的检测被广泛应用。A组链球菌细胞壁的M蛋白具有型特异性。检测抗M蛋白抗体非常重要，但由于M蛋白类型众多且纯化困难，将其应用于临床实践并不容易。C多肽具有组特异性，因此检测抗C多肽抗体作为A组链球菌的血清学检测非常重要。
